Oral Medroxyprogesterone in the Treatment of Dysfunctional Uterine Bleeding : A Preliminary Report

Abstract

The preliminary study of the effectiveness of oral medroxyprogesterone ace tate was conducted among seventeen women with dysfunctional uterine bleeding at Songklanagarind Hospital from September 1988 to August 1989. The patients were treated with a dosage of 10 mg (one tablet) daily for ten days as initial hormonal he mostasis. After the first withdrawal bleeding, the menstrual blood flow was regulated for the next three cycles at a dosage of 10 mg daily from day 15 to day 24 of the cycle. The patients were evaluated by subjective description (menstrual calendar) for continu ous observation (3 cycles after therapy). 

Twelve of the seventeen women (70.5 per cent) who had partial follow-up were satisfactory during treatment, and ten of the seventeen women (58.8 per cent) were sat isfactory during treatment and post treatment. There were no adverse drug reactions. (Thai J Obstet Gynaecol 1989 ; 1 :91-6.)