Treatment of Mucopurulent Cervicitis with Doxycycline

Abstract

The study of treatment of mucopurulent cervicitis with doxycycline hyclate was carried out among 56 patients attending the Sexually Transmitted Diseases Clinic, Songklanagarind Hospital, from January 1 to December 31, 1987 to evaluate its efficacy. Those patients with infections of N. gonorrhoeae, herpes simplex virus, C. albicans, T. vaginalis and non-specific vaginitis were excluded. The characteristics of mucopurulent cervicitis included the presence of yellowish endocervical secretion and the presence of 10 or more polymorphonuclear leukocytes per microscopic field of 1000 magnifications. The patients were given 200 mg doxycycline hyclate orally initially followed by 100 mg twice daily for 8 days. Their sexual partners were treated likewise. Those receiving anti biotics within 2 weeks, pregnant women and women during lactating period and prosti tutes were excluded from this treatment. A follow-up visit was scheduled 1-2 weeks after the completion of treatment. The results were, by self assessment, good and unchanged in 92.85 % and 7.14 % respectively. However, clinical evidence of yellowish endocervical secretion disappeared in 86.84 % with reduction of the presence of 10 or more polymor phonuclear leukocytes in 71.42 % (Thai J Obstet Gynecol 1989;1: 21-24)