Clinical and Metabolic Study of Triphasic Contraceptive Pill (Triquilar)®

Abstract

One hundred and forty healthy women were recruited for clinical and meta bolic study. Each woman was instructed to take a triphasic pill at bed time. Forty-two percent of the volunteers completed 24 cycles for a total of 1847 cycles. The cycle control was quite satisfactory and no accidental pregnancy occurred. Changes in blood pressure and body weight were insignificant during the trial. Three cases showed an abnormal glucose tolerance test at six and nine months after taking pill. Fasting state serum tran saminase, and bilirubin showed no sinificant changes of mean values, but significant de creases in alkaline phosphatase were observed at 3,6 and 12 months after taking the OC. Lipid metabolism, serum cholesterol, triglycerides and its fractions remained unchanged during treatment period. (Thai J Obstet Gynaecol 1989;1:31-38)