Twin Pregnancy Presenting with Hydatidiform Mole and Co-existing Living Fetus with Ovarian Venous Thrombosis: A case report
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Abstract
Background: This case was a twin pregnancy with a complete hydatidiform mole (CHM) and a co-existing fetus. Gestational trophoblastic neoplasia (GTN) and ovarian venous thrombosis (OVT) were diagnosed during the postpartum period.
Case: A 25-year-old pregnant woman, gravid 2, para1-0-0-1 presented with vaginal bleeding. Ultrasonography showed multi-cystic placenta separated from a normal placenta and a living fetus. The patient had a vaginal delivery at 31+5 weeks of gestation. Placental histology described a CHM and negative p57(kip2) immunohistochemistry. Post-molar GTN was diagnosed after one month of delivery. Low-risk GTN was diagnosed with OVT. Clinical symptoms subsided after administrating of single-agent methotrexate and an anticoagulant and without complication during one year follow-up.
Conclusion: CHM with a co-existing fetus needs imaging, prenatal genetics, and pathological plus p57 immunohistochemistry for diagnosis.
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