Correlation between 50-gram Glucose Challenge Test and Neonatal Birth Weight

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Published: Dec 29, 2017
DOI: https://doi.org/10.14456/tjog.2017.32

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Suntaree Tongchalam
Department of Obstetrics & Gynecology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand
Kamol Pataradool
Department of Obstetrics & Gynecology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand

Abstract

Objectives: To determine the correlation between the 50 gram glucose challenge test (50-g GCT) and neonatal birth weight.
Materials and Methods: The study comprised of 1879 women who underwent 50-g GCT at 24-28 weeks of gestation and delivered term infants. We determined the correlation between 50-g GCT by percentile and neonatal birth weight by using Pearson’s correlation. ROC analysis was used to determine the threshold of 50-g GCT for predicted low birth weight and macrosomia infants.
Results: The correlation coefficient between 50-g GCT by percentile and neonatal birth weight yielded a result of 0.885 (strong positive correlation). Using ROC analysis, 50-g GCT level ≥ 130 mg/dl predicted macrosomia infants with a sensitivity of 41%, specificity 72%, positive predictive value (PPV) 2% and negative predictive value (NPV) 99%. 50-g GCT level ≤ 105 mg/dl predicted low birth weight infants with a sensitivity of 40%, specificity 65%, PPV 6% and NPV 95% respectively.
Conclusion: There is a positive correlation between 50-g GCT and neonatal birth weight. 50-g GCT can be used as predictor for macrosomia infants and low birth weight infants.


Keywords: 50g glucose challenge test, neonatal birth weight.

Article Details

How to Cite
(1)
Tongchalam, S.; Pataradool, K. Correlation Between 50-Gram Glucose Challenge Test and Neonatal Birth Weight. Thai J Obstet Gynaecol 2017, 25, 242-248.
Issue
VOL. 25, NO. 4: (October - December 2017)
Section
Original Article

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