A Retrospective Study of Anti-HIV Seropositive Adolescent Parturients in Chonburi Hospital During 2001- 2006

Abstract

Objective To assess the prevalence of anti-HIV seropositive adolescent parturient and
maternal and neonatal outcomes.
Study design Retrospective descriptive study.
Materials and methods The study group consisted of pregnancy aged 14-21 years who had the
anti-HIV (ELISA) test positive and gave births at Chonburi Hospital from January 1, 2001 to
December 31, 2006. Demographic data, obstetric and neonatal informations were collected
from medical records.
Results Among the total 5,302 deliveries of adolescent pregnancy in Chonburi Hospital, fifty
cases with anti-HIV seropositive were found. The prevalence was 9.43 per 1000 cases.
Majority of these (40%) were in age group 20-21 years. Seventy four percent had 4 times or
more of antenatal care visits. The mean CD4 level during pregnancy was 448.4± 190.3
cells/mm3 and 74% received zidovudine during antenatal care. Only 22 newborns (44%)
could be followed up until 12 months, and only 1 baby was infected. Preterm labor and
premature rupture of the membranes were common obstetric complications. Most of them
had good neonatal outcomes. The average birth weight in antiretroviral drug receiving was
significant higher than in non-receiving groups (2,988.1 ± 384.5 versus 2,702± 394.5 grams,
P= 0.026). The number of antenatal care visits and CD4 level in antiretroviral drug receiving
group were also significant higher than in non-receiving group (7.5± 2.9 versus 2.9± 2.1
times, P<0.01 and 468.9± 180.2 versus 229.7± 183.9 cells/mm3, P= 0.035)
Conclusion The prevalence of anti-HIV seropositive adolescent parturient in Chonburi Hospital
was 9.43 per 1,000 cases. None of the mothers and fetuses had serious complications.