Comparison of The Survival Rate between Squamous Cell Carcinoma and Adenocarcinoma of the Uterine Cervix
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Abstract
Objective To compare the survival rate between squamous cell carcinoma (SCC) and
adenocarcinoma (ACA) of the uterine cervix.
Methods All medical records and pathological reports were reviewed. The patients who lost to follow up were contacted by telephone, mail, or computerized death data from local registration sector at BMA.
Results Five hundred and seventy three patients were studied. SCC, the most common
histologic type, was found in 79.23%. ACA including adenosquamous cell carcinoma and
other subtypes consisted of 20.77%. The mean age in ACA group was 47.85 + 10.99 years
which was significantly lower than 51.15 + 11.87 years of SCC group (p=0.006). Most patients
(65.9%) with SCC had tumor grade II but patients with ACA were commonly found in grade
III(42.0%). Regarding clinical presentation, ACA was found at earlier stages than SCC
(p<0.0001). About half of these patients with ACA had tumor characteristics as exophytic
mass(56.7%) whereas tumor of patients with SCC were mainly ulceroinfiltrative lesion(56.2%).
With the median follow up time of 51 months(range 0 – 110 months), the overall survival of
SCC was 61.34% and ACA was 62.27%(p =0.7467). Comparing the survival of SCC and ACA,
stage by stage, ACA had poorer survival rate in every stage, with no statistically significant
difference.
Conclusion SCC was the most common cell type in cervical carcinoma. The patients with SCC were older, and presented at more advanced stage than patients with ACA. The overall
survival of patients with both cell types were not significantly different.
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