Malignant Ovarian Germ Cell Tumor: Point for General OB-GYN

Abstract

Although relatively uncommon compared to
epithelial ovarian cancer, malignant ovarian germ cell
tumor (MOGCT) is the cancer that most patients could
be cured. The evolution of treatment during the past
two decades has been one of the true success stories
in oncology. Many recent advanced discoveries have
arisen from the studies of testicular cancer, which is
10- fold more common than ovarian germ cell tumor. (1)
MOGCT account for less than 5% of ovarian cancer. (1)
Their significance is greater than their numerical
implied incidence because they occur in children and
young women during their prime age. (2,3) Contrasting
dramatically with epithelial ovarian cancer, which
usually occurred in perimenopausal or postmenopausal
age. Since management for this cancer is definitely
different from epithelial ovarian cancer according to
age of the patient and as well as being chemosensitive
tumor itself. Fertility function is a major concern for
patients. This article is a review of current clinical
profiles, practical management and outcomes of
patients with MOGCT.