The treatment of Curcuma longa on rabbit dermatitis

Main Article Content

Charinya Pimson
Nuengruethai Parakhan
Patcharaporn Nantapet
Jiratti Thammasiri
Natedara Chanutsa
Peechanika Chopjitt

Abstract

Curcumin is one of the major components of Curcuma longa that has been reported to anti-inflammation, antioxidants, and anti-bacterial, especially Staphylococcus aureus. This study examines the anti-inflammatory and antioxidant effect of Curcumin against bacterial infection on rabbit skin. Fifteen rabbits were randomly divided into five groups as follows: un-infection and un-treatment with scarification, infection without treatment, treatments with 5% and 10% Curcuma longa creams and Tetracycline cream. Skin lesion of the rabbits was monitored for a week. The activities of antioxidant enzyme, level of total glutathione and lipid-peroxidation were examined to finally detect the oxidative stress. This study found that the activities of antioxidant systems and the level of lipid peroxidation was significantly reduced when we treated with Curcuma longa cream while level of total glutathione were gradually increased in skin rabbit. 10% Curcuma longa cream is the most effective. These findings imply that the effort of developing Curcumin into a therapeutic antibacterial skin and anti-resistant agent is reasonable.

Article Details

How to Cite
Pimson, C., Parakhan, N., Nantapet, P., Thammasiri, J., Chanutsa, N., & Chopjitt, P. (2018). The treatment of Curcuma longa on rabbit dermatitis. Veterinary Integrative Sciences, 16(1), 1–13. Retrieved from https://he02.tci-thaijo.org/index.php/vis/article/view/123245
Section
Research Articles

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