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Urinary tract infections (UTIs) are required antimicrobial prescription in small animal practice. The proper antimicrobial drug use is crucial for successfully treating UTIs in dogs. Several studies have reported the use of antimicrobials in dogs with UTIs. However, the report in tropical countries are lacking. The objectives of this study were to identify bacterial pathogens and to investigate antimicrobial susceptibility in dogs with UTIs. Dogs with suspected UTIs admitted at Veterinary Teaching Hospital (VTH), Khon Kaen University (KKU) between 2013-2017 were included in the present study. The urine samples were collected using either cystocentesis or sterile urinary catheterization. All urine samples were later submitted to the Veterinary Clinical Diagnostic Laboratory (VCDL) within 30 min. The samples were performed for bacterial identification and drug susceptibility tests. The most common bacterial isolates were Staphylococcus intermedius (33.58%, n = 46), Proteas mirabilis (27.01%, n = 37) and Escherichia coli (19.71%, n = 27), respectively. Among the gram-positive isolates, Staphylococcus intermedius was susceptibility to amoxycillin-clavulanic acid (86.36%) and tetracycline (89.47%), respectively. Proteus mirabilis was susceptibility to amoxicillin (86.12%) and enrofloxacin (67.64%) and E. coli was susceptibility to amikacin (100%), amoxycillin-clavulanic acid (77.77%). In conclusion, amoxycillin-clavulanic acid was the most antimicrobial susceptible to all bacterial isolates. However, emerging multi-drug resistance is of concern worldwide, antibiotics should be decided depending on culture and susceptibility test.
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Beyene, & Tsegaye. (2011). Bacterial Uropathogens in Urinary Tract Infection and Antibiotic Susceptibility Pattern in Jimma University Specialized Hospital, Southwest Ethiopia. Ethiop J Health Sci, 21(2), 141-146.
Bouillon, J., Snead, E., Caswell, J., Feng, C., Helie, P., & Lemetayer, J. (2017). Pyelonephritis in Dogs: Retrospective Study of 47 Histologically Diagnosed Cases (2005-2015). J Vet Intern Med, 32(1), 249-259.
Bubenik, L. J., Hosgood, G. L., Waldron, D. R., & Snow, L. A. (2007). Frequency of urinary tract infection in catheterized dogs and comparison of bacterial culture and susceptibility testing results for catheterized and noncatheterized dogs with urinary tract infections. J Am Vet Med Assoc, 231(6), 893-899.
Chang, Shao-Kuang, Lo, Dan-Yuan, Wei, Hen-Wei, Kuo, & Hung-Chih. (2015). Antimicrobial resistance of Escherichia coli isolates from canine urinary tract infections. J Vet Med Sci, 77(1), 59-65.
Cummings, J., K., Aprea, A., V., Altier, & Craig. (2015). Antimicrobial resistance trends among canine Escherichia coli isolates obtained from clinical samples in the northeastern USA, 2004–2011. Can Vet J, 56(4), 393-398.
Dowling, P. M. (1996). Antimicrobial therapy of urinary tract infections. Can Vet J, 37(7), 438-441.
Gatoria, I. S, Saini, N. S, Rai, T. S, Dwivedi, & P. N. (2006). Comparison of three techniques for the diagnosis of urinary tract infections in dogs with urolithiasis. J Small Anim Pract, 47(12), 727-732.
Gupta, K., Hooton, T. M., Naber, K. G., Wullt, B., Colgan, R., Miller, L. G., Moran, G. J., Nicolle, L. E., Raz, R., Schaeffer, A. J., & Soper, D. E. (2011). International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. Clin Infect Dis, 52(5), e103-120.
Hagman, R., & Greko, C. (2005). Antimicrobial resistance in Escherichia coli isolated from bitches with pyometra and from urine samples from other dogs. Vet Rec, 157(7), 193-196.
Hall, L., J., Holmes, A., M., Baines, & J., S. (2013). Prevalence and antimicrobial resistance of canine urinary tract pathogens. Vet Rec, 173(22), 549.
Hariharan, Harry, Brathwaite-Sylvester, Erica, Belmar, Matthew, V., Sharma, & Ravindra. (2016). Bacterial isolates from urinary tract infection in dogs in Grenada, and their antibiotic susceptibility. OJVM, 6(06), 85.
Hutchins, R. G., Vaden, S. L., Jacob, M. E., Harris, T. L., Bowles, K. D., Wood, M. W., & Bailey, C. S. (2014). Vaginal microbiota of spayed dogs with or without recurrent urinary tract infections. J Vet Intern Med, 28(2), 300-304.
Jessen, R., L., Sørensen, M., T., Bjornvad, R., C., Nielsen, Saxmose, S., Guardabassi, & L. (2015). Effect of antibiotic treatment in canine and feline urinary tract infections: A systematic review. Vet J, 203(3), 270-277.
Kroemer, S., El Garch, F., Galland, D., Petit, J.-L., Woehrle, F., & Boulouis, H.-J. (2014). Antibiotic susceptibility of bacteria isolated from infections in cats and dogs throughout Europe (2002–2009). Comp Immunol Microbiol Infect Dis, 37(2), 97-108.
Ling, V., G., Norris, R., C., Franti, E., C., Eisele, H., P., Johnson, L., D., Ruby, L., A., Jang, & S., S. (2001a). Interrelations of organism prevalence, specimen collection method, and host age, sex, and breed among 8,354 canine urinary tract infections (1969-1995). J Vet Intern Med, 15(4), 341-347.
Ling, V., G., Norris, R., C., Franti, E., C., Eisele, H., P., Johnson, L., D., Ruby, L., A., Jang, & S., S. (2001b). Interrelations of Organism Prevalence, Specimen Collection Method, and Host Age, Sex, and Breed among 8,354 Canine Urinary Tract Infections (1969–1995). J Vet Intern Med, 15(4), 341-347.
Moyaert, H., Morrissey, I., de Jong, A., El Garch, F., Klein, U., Ludwig, C., Thiry, J., Youala, & M. (2017). Antimicrobial Susceptibility Monitoring of Bacterial Pathogens Isolated from Urinary Tract Infections in Dogs and Cats Across Europe: ComPath Results. Microb Drug Resist, 23(3), 391-403.
Penna, Bruno, Varges, Renato, Martins, Rodrigo, Martins, Gabriel, Lilenbaum, & Walter. (2010). In vitro antimicrobial resistance of Staphylococci isolated from canine urinary tract infection. Can Vet J, 51(7), 738-742.
Thompson, F., M., Litster, L., A., Platell, L., J., Trott, & J., D. (2011). Canine bacterial urinary tract infections: New developments in old pathogens. Vet J, 190(1), 22-27.
Thungrat, K., Price, S., B., Carpenter, D., M., Boothe, & D., M. (2015). Antimicrobial susceptibility patterns of clinical Escherichia coli isolates from dogs and cats in the United States: January 2008 through January 2013. Vet Microbiol, 179(3-4), 287-295.
Weese, S., J., Blondeau, M., J., Boothe, D., Breitschwerdt, B., E., Guardabassi, L., Hillier, A., Lloyd, H., D., Papich, G., M., Rankin, C., S., Turnidge, D., J., Sykes, & E., J. (2011). Antimicrobial Use Guidelines for Treatment of Urinary Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases. Vet Med Int, 2011, 263768.
Weese, S., J., Giguere, S., Guardabassi, L., Morley, S., P., Papich, M., Ricciuto, R., D., Sykes, & E., J. (2015). ACVIM consensus statement on therapeutic antimicrobial use in animals and antimicrobial resistance. J Vet Intern Med, 29(2), 487-498.
Westropp, L., J., Sykes, E., J., Irom, S., Daniels, B., J., Smith, A., Keil, D., Settje, T., Wang, Y., Chew, & J., D. (2012). Evaluation of the efficacy and safety of high dose short duration enrofloxacin treatment regimen for uncomplicated urinary tract infections in dogs. J Vet Intern Med, 26(3), 506-512.
Windahl, Ulrika, Holst, Bodil, Nyman, Ann-Kristin, Grönlund, Ulrika, Bengtsson, & Björn. (2014). Characterisation of bacterial growth and antimicrobial susceptibility patterns in canine urinary tract infections. BMC Vet Res, 10(1), 217.
Wong, C., Epstein, E., S., Westropp, & L., J. (2015). Antimicrobial Susceptibility Patterns in Urinary Tract Infections in Dogs (2010-2013). J Vet Intern Med, 29(4), 1045-1052.