Occupational health for laboratory workers involved in the care and use of Long-tailed macaque(Macaca fascicularis)
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Abstract
tLong-tailed macaque (Macaca fascicularis) play an important role in public health worldwide as they are often used in many drug and vaccine research studies. The recently established National Primate Research Centre (NPRC) of Thailand aims to breed a large number of Long-tailed macaque for research purposes. However, this breeding program may increases the risk of communicable diseases between the Long-tailed macaque population and NPRC staff. Currently, there are no specific occupational standards or guidelines for laboratory workers involved in the care and use of Long-tailed macaque. The creation of occupational health guidelines and recommendations for NPRC staff will be based on a thorough occupational health risk assessment process including information on currently known high risk pathogens. Based on current research, the major pathogens identified as a transmission risk from Long-tailed macaque to humans are B virus, simian retroviruses, hepatitis virus, rabies virus and tetanus; while tuberculosis, measles, influenza viruses and enteric bacterial pathogens comprise the highest risk of pathogens transfer from humans to Long-tailed macaque. In order to prevent these transmissions, appropriate vaccination programs for both humans and Long-tailed macaque population will be required, along with annual occupational health risk assessment reviews for NPRC staff and its operating practices. Achieving and maintaining optimal health and minimal risks for NPRC staff and Long-tailed macaque requires the collaboration of many occupations such as medical doctors, veterinarians, and support staff, jointly operating under the principle of One Health.
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