Canine degenerative myelopathy in Welsh Corgi
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Abstract
This is the first report of Canine degenerative myelopathy (DM) in northern Thailand. Canine degenerative myelopathy is a progressive, fatal disease. The clinical signs are included proprioceptive ataxia, paraplegia and progress to quadriplegia. The dog will die within three years after clinical signs were appearance. The diagnosis of DM needs to complete neurological examination; postmortem histopathology was definitive diagnosis. There is currently no cure for DM. This case was reported in Welsh Corgi which had been diagnosed by neurological examination including Magnetic resonance imaging. The DNA test for DM was performing to detect mutation of Superoxide dismutase 1 (SOD1) which is one of etiology of the disease. Although DNA testing was not definitive diagnosed, it can be used for screening tests for breeding plan in dogs.
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