Association of FTH and EPOR gene polymorphisms with litter size traits in pigs https://doi.org/10.12982/VIS.2022.023

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Published: Feb 25, 2022
Keywords:
EPOR FTH Litter size Pig Polymorphisms

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Supamit Mekchay
Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand, Center of Excellence on Agricultural Biotechnology: (AG-BIO/MHESI), Bangkok 10900, Thailand , Cluster of Research and Development of Pharmaceutical and Natural Products Innovation for Human or Animal, Chiang Mai University, Chiang Mai 50200, Thailand, Innovative Agriculture Research Center, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand
Worrarak Norseeda
Department of Agriculture, Faculty of Agricultural Technology, Lampang Rajabhat University, Lampang 52100, Thailand
Nanthana Pothakam
Veterinary, Conservation and Research Section, Animal Management Division, Chiang Mai Night Safari, Chiang Mai 50230, Thailand
Guisheng Liu
Institute of Animal Science and Veterinary Medicine, Hubei Academy of Agricultural Sciences, Wuhan 430064, China, Hubei Key Lab for Animal Embryo Engineering and Molecular Breeding, Wuhan 430064, China
Tawatchai Teltathum
Mae Hong Son Livestock Research and Breeding Center, Mae Hong Son 58000, Thailand
Korawan Sringarm
Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand, Cluster of Research and Development of Pharmaceutical and Natural Products Innovation for Human or Animal, Chiang Mai University, Chiang Mai 50200, Thailand
Watcharapong Naraballobh
Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand, Innovative Agriculture Research Center, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand
Trisadee Khamlor
Department of Animal and Aquatic Sciences, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand
Patcharin Krutmuang
Innovative Agriculture Research Center, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand, Department of Entomology and Plant Pathology, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand

Abstract

Ferritin heavy chain (FTH) and erythropoietin receptor (EPOR) are responsible for the iron homeostasis and the erythropoiesis that correlate to the reproductive systems. This study aimed to examine an association of the porcine FTH and EPOR genes with litter size traits in Large White and Landrace pigs. The porcine FTH g.9537834G > A was significantly associated with the total number born (TNB) trait in these pig populations (p < 0.05). The porcine FTH g.9537855T > C was significantly associated with the TNB trait in Large White sows (p < 0.05) as well as the TNB and the number of birth alive (NBA) traits in Landrace sows (p < 0.05). The porcine EPOR g.70066473C > T was significantly associated with the TNB trait in Large White sows (p < 0.05) as well as the TNB, NBA, and the number of piglets weaned alive (NWA) traits in Landrace sows (p < 0.05). Moreover, the accumulated favorable alleles of these three SNPs were increasingly associated with TNB trait in Large White sows (p < 0.05) and TNB, NBA, and NWA traits in Landrace sows (p < 0.05). These findings suggest that porcine FTH and EPOR genes may contribute to the reproductive processes of pigs with regards to litter size and confirm the importance of these genes as candidate genes for improving litter size in pigs

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How to Cite
Mekchay, S. ., Norseeda, W. ., Pothakam, N. ., Liu, G. ., Teltathum, T. ., Sringarm, K. ., Naraballobh, W. ., Khamlor, T. ., & Krutmuang, P. . (2022). Association of FTH and EPOR gene polymorphisms with litter size traits in pigs : https://doi.org/10.12982/VIS.2022.023. Veterinary Integrative Sciences, 20(2), 291–308. Retrieved from https://he02.tci-thaijo.org/index.php/vis/article/view/256374
Issue
Vol. 20 No. 2 (2022): May-August
Section
Research Articles
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