Anthelmintic efficacy of mango seed extract on porcine gastrointestinal nematodes https://doi.org/10.12982/VIS.2022.038
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Abstract
The usual control for gastrointestinal parasites is the use of commercial anthelmintics. However, parasites are becoming more resistant due to the frequent and inappropriate use of these anthelmintics. As a result, alternatives for these anthelmintics are becoming increasingly widespread for deworming livestock, particularly those that come from natural sources. Thus, this study aimed to evaluate the efficacy of mango (var. Carabao) seed extract in reducing the egg per gram counts of common gastrointestinal nematodes in pigs and compare the efficacy with that of levamisole. Experimental animals were naturally infected pigs with Trichuris spp. and Strongyloides spp. being the most predominant. The animals were administered orally with a single dose of the mango seed extract at concentrations of 600, 700, and 800 mg per kg bodyweight. The extract, regardless of concentration, was able to decrease the epg counts. Within 14 days post-treatment, there was no significant difference in the efficacies in the administration of 800 mg extract per kg bodyweight and levamisole. This comparable efficacy was sustained until 28 days post-treatment. This significant in vivo anthelmintic activity may be attributed to the tannins and flavonoids present in the extract. These results indicate that the mango seed
extract is effective in controlling and reducing the gastrointestinal nematodes in pigs and may have the potential to be further developed as an anthelmintic.
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