Natural and recombinant equine chorionic gonadotropins past and future in animal reproductive technology https://doi.org/10.12982/VIS.2022.058

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Published: Oct 17, 2022
Keywords:
Chorionic gonadotropin Equine CG Fertility control Glycoprotein hormone Gonadotropins

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Duong Tien Thach
Faculty of Natural Sciences, Quy Nhon University, Binh Dinh 550000, Vietnam Graduate University of Science and Technology, Vietnam Academy of Science and Technology, Ha Noi 100000, Vietnam
Bui Khac Cuong
Laboratory Animal Research Center, Vietnam Military Medical University, Ha Noi 100000, Vietnam
Hoang Van Tong
Institute of Biomedicine and Pharmacy, Vietnam Military Medical University, Ha Noi 100000, Vietnam
Vo Van Chi
Faculty of Natural Sciences, Quy Nhon University, Binh Dinh 550000, Vietnam
Ngo Kim Khue
Faculty of Natural Sciences, Quy Nhon University, Binh Dinh 550000, Vietnam
Nguyen Thi Phuong Hien
Faculty of Natural Sciences, Quy Nhon University, Binh Dinh 550000, Vietnam
Nong Van Hai
Institute of Genome Research, Vietnam Academy of Science and Technology, Ha Noi 100000, Vietnam Graduate University of Science and Technology, Vietnam Academy of Science and Technology, Ha Noi 100000, Vietnam
Yves Combarnous
INRAe, CNRS, Tours University Joint Unit, Physiologie de la Reproduction et des Comportements, Nouzilly 37380, France
Thi Mong Diep Nguyen
Faculty of Natural Sciences, Quy Nhon University, Binh Dinh 550000, Vietnam

Abstract

Equine Chorionic Gonadotropin (eCG) previously named Pregnant Mare Serum Gonadotropin (PMSG) has been widely used since the 40s in animal reproduction control. It is extracted from the blood of pregnant mares between days 40 and 120 of gestation. Animal welfare organizations have voiced concerns against mares bleeding conditions. There is currently no effective substitute for the natural PMSG. In this review, we summarize the basic knowledge of the structure and biology of eCG, and the research on recombinant eCG production in the past five years.

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How to Cite
Tien Thach, D. ., Khac Cuong, B. ., Van Tong, H. ., Van Chi, V. ., Kim Khue, N. ., Thi Phuong Hien, N. ., Van Hai, N. ., Combarnous, Y. ., & Mong Diep Nguyen, T. . (2022). Natural and recombinant equine chorionic gonadotropins past and future in animal reproductive technology: https://doi.org/10.12982/VIS.2022.058. Veterinary Integrative Sciences, 20(3), 751–760. Retrieved from https://he02.tci-thaijo.org/index.php/vis/article/view/259739
Issue
Vol. 20 No. 3 (2022): September-December
Section
Review Article
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