Blood biochemistry and stress biomarkers of broiler chickens supplemented with different levels of Yucca schidigera saponins reared under tropical conditions https://doi.org/10.12982/VIS.2023.001
Article Sidebar
Main Article Content
Abstract
The primary goal of this study was to determine the impacts of supplementing varying amounts of Y. schidigera saponins on the blood biochemistry and stress biomarkers of broiler chickens raised in tropical settings. A total of 300 male day-old Ross 308 broilers were randomly assigned to six treatment groups. Treatment 1 broiler chickens were fed commercial diets with no added additives, whereas treatment 2 broiler chickens were offered commercial diets containing 100 mg/kg of the antibiotic oxytetracycline. Treatments 3, 4, 5, and 6 broiler chickens received similar commercial diets supplemented with 25, 50, 75, and 100 mg/kg of powdered Y. Shidigera saponins, respectively, without antibiotics. On day 42, six broilers from each treatment were randomly selected, slaughtered, and blood samples were collected for serum lipid profile, liver function,acute phase proteins, hormone, and heat shock protein analyses. There were notable changes (P < 0.05) in the serum lipid profile, acute phase proteins, hormone, and heat shock protein among treatments. Broilers treated with 100 mg/kg of Y.Shidigera saponins in T6 showed the lowest levels of cholesterol, triglycerides, and low-density lipoprotein cholesterol concentrations while having the highest high-density lipoprotein cholesterol level without affecting the liver parameters. Moreover, the serum amyloid A, alpha-1-acid glycoprotein, corticosterone, and heat shock protein 70 concentrations were
also the lowest as compared to the other treatments. In conclusion, supplementing 100 mg/kg of Y. Shidigera saponins in broiler diets could improve lipid profiles and act as an anti-stress for commercial broilers raised in tropical regions.
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
Publishing an article with open access in Veterinary Integrative Sciences leaves the copyright with the author. The article is published under the Creative Commons Attribution License 4.0 (CC-BY 4.0), which allows users to read, copy, distribute and make derivative works from the material, as long as the author of the original work is cited.
References
Abo Ghanima, M.M., Swelum, A.A., Shukry, M., Ibrahim, S.A., Abd El-Hack, M.E.,Khafaga, A.F., Alhimaidi, A.R., Ammari, A.A., El-Tarabily, K.A., Younis, M.E.M.,2021. Impacts of tea tree or lemongrass essential oils supplementation on growth,immunity, carcass traits, and blood biochemical parameters of broilers reared under different stocking densities. Poult Sci. 100(11), 101443.
Afrose, S., Hossain, M.S., Tsujii, H., 2010. Effect of dietary karaya saponin on serum and egg yolk cholesterol in laying hens. Br. Poult. Sci. 51, 797-804.
Alghirani, M.M., Chung, E.L.T., Jesse, F.F.A., Sazili, A.Q., Loh, T.C., 2022. The potential use of plant-derived saponins as a phytobiotic additive in poultry feed for production and health advancement: a comprehensive review. Poult. Sci. J. 10, 215-226.
Alghirani, M.M., Chung, E.L.T., Jesse, F.F.A., Sazili, A.Q., Loh, T.C., 2021b. Could phytobiotics replace antibiotics as feed additives to stimulate production performance and health status in poultry? An overview. J. Adv. Vet. Res. 11,254-265.
Alghirani, M.M., Chung, E.L.T., Sabri, D.S.M., Tahir, M., Kassim, N.A., Kamalludin, M.H.,Nayan, N., Jesse, F.F.A., Sazili, A.Q., Loh, T.C., 2021a. Can Yucca schidigera be used to enhance the growth performance, nutrient digestibility, gut histomorphology, cecal microflora, carcass characteristic, and meat quality of commercial broilers raised under tropical conditions?. Animals (Basel). 11(8), 2276.
Ariana, M., Samie, A., Edriss, M.A., Jahanian, R., 2011. Effects of powder and extract form of green tea and marigold, and-tocopheryl acetate on performance, egg quality and egg yolk cholesterol levels of laying hens in late phase of production. J. Med. Plant. Res. 5, 2710-2716.
Basit, M.A., Kadir, A.A., Loh, T.C., Abdul Aziz, S., Salleh, A., Zakaria, Z.A., Banke Idris, S., 2020. Comparative efficacy of selected phytobiotics with halquinol and tetracycline on gut morphology, ileal digestibility, cecal microbiota composition and growth performance in broiler chickens. Animals (Basel). 10(11), 2150.
Bera, I., Tyagi, P.K., Mir, N.A., Tyagi, P.K., Dev, K., Sharma, D., Mandal, A.B., 2019. Dietary supplementation of saponins to improve the quality and oxidative stability of broiler chicken meat. J. Food Sci. Technol. 56, 2063-2072.
Boripun, R., Paopradit, P., Prampramote, J., Narinthorn, R., Intongead, S., Sangkanu, S.,Narongrit, T., Mitsuwan, W., 2022. Bactericidal activity of Piper betle L. extract against antibiotic resistant Salmonella spp. isolated from pig farms in Southern Thailand. Vet. Integr. Sci. 20, 557-569.
Chaudhary, S.K., Bhar, R., Mandal, A.B., Rokade, J.J., Jadhav, S.E., Kannan, A., Gopi, M., 2018. Effect of dietary soapnut (Sapindus mukorossi) shell powder on selected stress indices, lipid profile and litter quality in broiler breeders. Anim. Nutr. Feed Technol.18, 311-320.
Chung, E.L.T., Alghirani, M.M., Kamalludin, M.H., Nayan, N., Jesse, F.F.A., Wei, O.T.A.,Stephen, M.A.F.M.H., Reduan, M.F.H., Loh, T.C., 2021. Do different vaccination regimes affect the growth performance, immune status, carcase characteristics and meat quality of broilers?. Br. Poult. Sci. 62(1), 32-37.
Chung, E.L.T., Jesse, F.F.A., Marza, A.D., Ibrahim, H.H., Abba, Y., Zamri-Saad, M., Haron, A.W., Lila, M.A.M., Saharee, A.A., Omar, A.R., Bakar, M.Z.A., Norsidin, M.J.,2019. Responses of pro-inflammatory cytokines, acute phase proteins and cytological analysis in serum and cerebrospinal fluid during haemorrhagic septicaemia infection in buffaloes. Trop. Anim. Health Prod. 51, 1773-1782.
Dunkley, C.S., McReynolds, J.L., Dunkley, K.D., Kubena, L.F., Nisbet, D.J., Ricke, S.C.,2007. Molting in Salmonella Enteritidis-challenged laying hens fed alfalfa crumbles. III. Blood plasma metabolite response. Poult. Sci. 86, 2492-2501.
Figueiredo, D., Gertler, A., Cabello, G., Decuypere, E., Buyse, J., Dridi, S., 2007. Leptin downregulates heat shock protein-70 (HSP-70) gene expression in chicken liver and hypothalamus. Cell Tissue Res. 329, 91-101.
Ghaedi, M., Zeinali, N., Ghaedi, A.M., Teimuori, M., Tashkhourian, J., 2014. Artificial neural network-genetic algorithm-based optimization for the adsorption of methylene blue and brilliant green from aqueous solution by graphite oxide nanoparticle. Spectrochim. Acta A: Mol. Biomol. Spectrosc. 125, 264-277.
Gilani, S.M.H., Zehra, S., Galani, S., Ashraf, A., 2018. Effect of natural growth promoters on immunity, and biochemical and haematological parameters of broiler chickens.Trop. J. Pharm. Res. 17, 627-633.
Greene, E.S., Emami, N.K., Dridi, S., 2021. Research Note: Phytobiotics modulate the expression profile of circulating inflammasome and cyto (chemo) kine in whole blood of broilers exposed to cyclic heat stress. Poult. Sci. 100, 100801.
Gruys, E., Toussaint, M.J., Upragarin, N., Ederen, V.A.M., Adewuyi, A.A., Candiani, D.,Nguyen, T.K.A., Sabeckiene, J., 2005. Acute phase reactants, challenge in the near future of animal production and veterinary medicine. J. Zhejiang Univ. Sci. B. 6(10),941-947.
Hajati, H., Hassanabadi, A., Golian, A., Nassiri-Moghaddam, H., Nassiri, M.R., 2015. The effect of grape seed extract and vitamin C feed supplementation on some blood parameters and HSP70 gene expression of broiler chickens suffering from chronic heat stress. Ital. J. Anim. Sci. 14, 3273.
Haryanto, A., Miharja, K., Vijayanti, N., 2016. Ratio and Blood Lipid Profile of Broiler Chickens. Int. J. Poult. Sci. 15, 27-34.
Hashemi, S.R., Davoodi, H., 2011. Herbal plants and their derivatives as growth and health promoters in animal nutrition. Vet. Res. Commun. 35, 169-180.
He, G., Zhao, L., Shishir, M.S.R., Yang, Y., Li, Q., Cheng, L., Guo, A., 2021. Influence of alfalfa meal, as a source of dietary fibre, on growth performance, development, pH of gastrointestinal tract, blood biochemical profile, and meat quality of broilers. J.Appl. Anim. Res. 49, 431-439.
Humam, A.M., Loh, T.C., Foo, H.L., Izuddin, W.I., Zulkifli, I., Samsudin, A.A., Mustapha,N.M., 2021. Supplementation of postbiotic RI11 improves antioxidant enzyme activity, upregulated gut barrier genes, and reduced cytokine, acute phase protein, and heat shock protein 70 gene expression levels in heat-stressed broilers. Poult. Sci.100, 100908.
Imik, H., Ozlu, H., Gumus, R., Atasever, M.A., Urcar, S., Atasever, M., 2012. Effects of ascorbic acid and α-lipoic acid on performance and meat quality of broilers subjected to heat stress. Br. Poult. Sci. 53(6), 800-808.
Janmohammadi, A., Sheikhi, N., Nazarpak, H.H., Brujeni, N.G., 2020. Effects of vaccination on acute-phase protein response in broiler chicken. Plos one 15, e0229009.
Khadem, A., Soler, L., Everaert, N., Niewold, T.A., 2014. Growth promotion in broilers by both oxytetracycline and Macleaya cordata extract is based on their antiinflammatory properties. Br. J. Nutr. 112, 1110-1118.
Lee, Y., Lee, S.H., Gadde, U.D., Oh, S.T., Lee, S.J., Lillehoj. H.S., 2017. Dietary Allium hookeri reduces inflammatory response and increases expression of intestinal tight junction proteins in LPS-induced young broiler chicken. Res. Vet. Sci. 112, 149-155.
Marques, L.R., Diniz, T.A., Antunes, B.M., Rossi, F.E., Caperuto, E.C., Lira, F.S., Goncalves, D.C., 2018. Reverse cholesterol transport: molecular mechanisms and the nonmedical approach to enhance HDL cholesterol. Front. Physiol. 9, 526.
Matsuura, H., 2001. Saponins in garlic as modifiers of the risk of cardiovascular disease.Nutr. J. 131, 1000-1005.
Ming, J., Xie, J., Xu, P., Liu, W., Ge, X., Liu, B., He, Y., Cheng, Y., Zhou, Q., Pan, L., 2010. Molecular cloning and expression of two HSP70 genes in the Wuchang bream (Megalobrama amblycephala Yih). Fish Shellfish Immunol. 28, 407-418.
Najafi, P., Zulkifli, I., Jajuli, A.N., Farjam, A.S., Ramiah, S.K., Amir, A.A., O'Reilly, E.L.,Eckersall, D., 2015. Environmental temperature and stocking density effects on acute phase proteins, heat shock protein 70, circulating corticosterone and performance in broiler chickens. Int. J. Biometeorol. 59, 1577-1583.
Nazifi, S., Dadras, H., Hoseinian, S.A., Ansari-Lari, M., Masoudian, M., 2010. Measuring acute phase proteins (haptoglobin, ceruloplasmin, serum amyloid A, and fibrinogen) in healthy and infectious bursal disease virus-infected chicks. Comp. Clin. Path. 19,283-286.
Ngamukote, S., Makynen, K., Thilawech, T., Adisakwattana, S., 2011. Cholesterol-lowering activity of the major polyphenols in grape seed. Molecules. 16, 5054-5061.
Norkeaw, R., Arjin, C., Sartsook, A., Hnokeaw, P., Thongkham, M., Detruengsri, B.,Chaiwang, N., Mekchay, S., Yano, T., Sringarm, K., 2022. Effect of dietary green tea extract supplementation in growing-finishing pigs on growth performance, meat quality, and oxidative stability of pork. Vet. Integr. Sci. 20, 571-583.
Paul, S., Islam, M., Tanvir, E.M., Ahmed, R., Das, S., Rumpa, N.E., Hossen, M.S., Parvez,M., Gan, S.H., Khalil, M., 2016. Satkara (Citrus macroptera) fruit protects against acetaminophen-induced hepatorenal toxicity in rats. Evid. Based Complement Alternat. Med. 2016, 9470954.
Reyno, S.R.T., Gonzaga, L.J.A., Gonzaga, E.A., 2022. Anthelmintic efficacy of mango seed extract on porcine gastrointestinal nematodes. Vet. Integr. Sci. 20, 507-515.
Rokade, J.J., Bhanja, S.K., Shinde, A.S., Sajad, S., Kapgate, M., Mandal, A.B., 2016. Evaluation of mannan-oligosaccharides (MOS) in broiler chicken during hot humid summer using zoo technical, molecular and physio-biochemical tools. Indian J. Anim. Sci. 86(4), 460-467.
Sandner, G., Mueller, A.S., Zhou, X., Stadlbauer, V., Schwarzinger, B., Schwarzinger, C.,Wenzel, U., Maenner, K., Klis, J.D.V., Hirtenlehner, S., Aumiller, T., Weghuber, J.2020. Ginseng extract ameliorates the negative physiological effects of heat stress by supporting heat shock response and improving intestinal barrier integrity: Evidence from studies with heat-stressed Caco-2 cells, C. elegans and growing broilers.
Molecules. 25, 835.
Strimbu, K., Tavel, J.A., 2010. What are biomarkers?. Curr. Opin. HIV. AIDS. 5(6), 463-466.
Tokofai, B.M., Idoh, K., Oke, O.E., Agbonon, A., 2021. Hepatoprotective effects of Vernonia amygdalina (Astereaceae) extract on CCI(4)-induced liver injury in broiler chickens. Animals (Basel). 11(12), 3371.
Zulkifli, I., Akmal, A.F., Soleimani, A.F., Hossain, M.A., Awad, E.A., 2018. Effects of low-protein diets on acute phase proteins and heat shock protein 70 responses, and growth performance in broiler chickens under heat stress condition. Poult. Sci. 97(4),1306-1314.