Efficacy of Mycotoxin Binder on Broiler Performance, Organ Weight, Wishbone Weight, and Gut Length: A Meta-Analysis https://doi.org/10.12982/VIS.2024.026
Article Sidebar
Main Article Content
Abstract
Mycotoxin-contaminated feed is one of the main causes of contamination that may increase broiler mortality and impair their production. A total of 161 in vivo data acquired from 31 published articles were used as a database for determining the effectiveness of mycotoxin binders on performance and health of broiler. The Hedges’ d value was employed as a measure of effect size (ES) in the present meta-analysis. Increasing mycotoxin binder in feed enhanced body weight (ES=0.784; P<0.001), decreased feed conversion ratio (ES=-0.87; P<0.001), and decreased mortality (ES=-3.98; P<0.001). In terms of average daily gain and mortality suppression, the finisher phase demonstrated the greatest effectiveness of the binder usage compared to the starter and finisher phases. The effectiveness of binders in lowering the incidence of mycotoxin in feed was beneficial in reducing mortality and enhancing broiler performance. In addition, its application into feed may enhance the health condition of broilers by enhancing organ weights and gastrointestinal health.
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
Publishing an article with open access in Veterinary Integrative Sciences leaves the copyright with the author. The article is published under the Creative Commons Attribution License 4.0 (CC-BY 4.0), which allows users to read, copy, distribute and make derivative works from the material, as long as the author of the original work is cited.
References
Abdurofi, I., Ismail, M.M., Kamal, H., Gabdo, B., 2017. Economic analysis of broiler production in peninsular malaysia. Int. Food Res. J. 24(2), 761-766.
Arafat, R.Y., Khan, S.H., 2017. Evaluation of humic acid as an aflatoxin binder in broiler chickens. Ann. Anim. Sci. 17(1), 241-255.
Awad, W.A., Ghareeb, K., Dadak, A., Hess, M., Böhm, J., 2014. Single and combined effects of deoxynivalenol mycotoxin and a microbial feed additive on lymphocyte DNA damage and oxidative stress in broiler chickens. PLoS. One. 9(1), e88028.
Basalan, M., Gungor, T., Aydogan, I., Hismiogullari, S.E., Erat, S., Erdem, E., 2006. Effects of feeding mycotoxin binder (HSCAS) at later ages on gastrointestinal environment and metabolism in broilers. Arch. Zootech. 9(1), 5-9.
Bindhu, L.V., Jin, K.T., Agrifoods, K., 2010. Mycotoxin binders-evaluation of efficiency by the in vitro method. J. Int. Poult. Prod. 18(1), 13-15.
Cheung, M.W., Vijayakumar, R., 2016. A guide to conducting a meta-analysis. Neuropsychol.Rev. 26(2), 121-128.
DerSimonian, R., Laird, N., 1986. Meta-analysis in clinical trials. Control Clin Trials. 7(3),177-188.
El-Katcha, M.I., Soltan, M.A., El-Shobokshy, S.A., Shokry, A., 2017. Protective effect of chemical and biological mycotoxin binder on growth performance, serum biochemistry and carcass traits in broiler chicks fed on aflatoxin contaminated diet. Alex. J. Vet. Sci. 55(1), 180-197.
Farooqui, M., Khalique, A., Rashid, M., Mehmood, S., Malik, M., 2019. Aluminosilicates and yeast-based mycotoxin binders: Their ameliorated effects on growth, immunity and serum chemistry in broilers fed aflatoxin and ochratoxin. S. Afr. J. Anim. Sci.
(4), 619-627.
Feshanghchi, M., Baghban-Kanani, P., Kashefi-Motlagh, B., Adib, F., Azimi-Youvalari, S.,Hosseintabar-Ghasemabad, B., Slozhenkina, M., Gorlov, I., Zangeronimo, M.G.,Swelum, A.A., 2022. Milk thistle (Silybum marianum), marine algae (spirulina
platensis) and toxin binder powders in the diets of broiler chickens exposed to aflatoxin-b1: Growth performance, humoral immune response and cecal microbiota. Agriculture. 12(6), 805.
García, A.R., Avila, E., Rosiles, R., Petrone, V.M., 2003. Evaluation of two mycotoxin binders to reduce toxicity of broiler diets containing ochratoxin a and t-2 toxin contaminated grain. Avian. Dis. 47(3), 691-699.
Ghazalah, A.A., Abd-Elsamee, M.O., Moustafa, K., Khattab, M.A., Rehan, A.A.A., 2021. Effect of nanosilica and bentonite as mycotoxins adsorbent agent in broiler chickens'diet on growth performance and hepatic histopathology. Animals (Basel). 11(7), 2129.
Hedayati, M., Manafi, M., Yari, M., 2014a. Aflatoxicosis in broilers: Efficacy of a commercial mycotoxin binder on performance and immunity parameters. Int. J.Ecosyst. 4(4), 176-183.
Hedayati, M., Manafi, M., Yari, M., Mousavipour, S., 2014b. Commercial broilers exposed to aflatoxin B1: Efficacy of a commercial mycotoxin binder on internal organ weights, biochemical traits and mortality. Int. J. Agric. For. 4(5), 351-358.
Hedayati, M., Manafi, M., Yari, M., Mousavipour, S., 2014c. Commercial broilers exposed to aflatoxin b1: Efficacy of a commercial mycotoxin binder on internal organ weights, biochemical traits and mortality. Int J Agric For. 4(5), 351-358.
Heidari, M., Sadeghi, A., Rezaeipour, V., 2018. Effects of acidifier supplementation and toxin binder on performance, carcass, blood metabolites, intestinal morphology, and microbial population in broiler chickens. Iranian Iran. J. Appl. Anim. Sci. 8(3), 469-476.
Issad, N.A., Mimoune, N., Ammari, C., Hammouni, R., Houari, C., Khelef, D., 2022. Effects of a toxin binder and an organic acidifier on the zootechnical performance of broiler chickens. Vet. Stanica. 53(6), 689-698.
Istiqomah, L., Damayanti, E., Julendra, H., Suryani, A.E., Sakti, A.A., Anggraeni, A.S., 2017.Effect of methionine and lactic acid bacteria as aflatoxin binder on broiler performance. In: AIP Conference Proceedings. 1854, 020017.
Kehinde, H., Sekoni, A., Olugbemi, T., Onimisi, P., 2018. Prevalence of aflatoxin b1 in some common poultry feed ingredients and optimum inclusion levels of mycofix binder as feed additive on performance of broiler chickens chickens. Niger. J. Anim. Prod.45(2), 137-149.
Kihal, A., Rodriguez-Prado, M., Godoy, C., Cristofol, C., Calsamiglia, S., 2020. In vitro assessment of the capacity of certain mycotoxin binders to adsorb some amino acids and water-soluble vitamins. J. Dairy. Sci. 103(4), 3125-3132.
Lai, Y., Sun, M., He, Y., Lei, J., Han, Y., Wu, Y., Bai, D., Guo, Y., Zhang, B., 2022. Mycotoxins binder supplementation alleviates aflatoxin B1 toxic effects on the immune response and intestinal barrier function in broilers. Poult. Sci. 101(3),101683.
Lee, S., Kim, D.H., Keum, M.C., Han, E., An, B.K., Chang, H.H., Choi, Y.H., Moon, B.H.,Lee, K.W., 2018. Effects of fumonisin B1 and mycotoxin binders on growth performance, tibia characteristics, gut physiology, and stress indicators in broiler chickens raised in different stocking densities. Poult. Sci. 97(3), 845-854.
Liberati, A., Altman, D.G., Tetzlaff, J., Mulrow, C., Gøtzsche, P.C., Ioannidis, J.P., Clarke, M., Devereaux, P.J., Kleijnen, J., Moher, D., 2009. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare
interventions: Explanation and elaboration. BMJ. 339, b2700.
Magnoli, A.P., Poloni, V.L., Cavaglieri, L., 2019. Impact of mycotoxin contamination in the animal feed industry. Curr. Opin. Food Sci. 29, 99-108.
Mimoune, N., Houari, C., Ammari, C., Hammouni, R., Ait Issad, N., Khelef, D., 2023.Zootechnical, bacteriological, and histometrical effects of a combination mycotoxin binder-acidifier in broiler chickens. Vet. Stanica. 54(1), 13-28.
Montagne, L., Pluske, J.R., Hampson, D.J., 2003. A review of interactions between dietary fibre and the intestinal mucosa, and their consequences on digestive health in young non-ruminant animals. Anim. Feed Sci. Technol. 108(1), 95-117.
Nabi, H., Hussain, I., Adil, M., Nasir, A., Sikandar, A., Khan, S., Khan, N., 2018. Impact of mycotoxin binders on humoral immunity, lymphoid organs and growth performance of broilers. Pak. J. Zool. 50(5), 1611-1618.
Nalle, C.L., Angi, A.A., Supit, M.A., Ambarwati, S., Yuliani, N.S., 2019. Response of broiler chickens fed on diets containing low level of aflatoxin (B1 and B2) and supplemented with mycotoxin binder. Prosiding Seminar Nasional Ke-7. 98-102.
Nalle, C.L., Supit, M.A.J., Bere, I.J.R., Hawu, R., The efficacy of mycosorb in broiler diets contaminated with low doses of aflatoxin B1. Buletin Peternakan. 45(3), 159-169.
Nazarizadeh, H., Pourreza, J., 2019. Evaluation of three mycotoxin binders to prevent the adverse effects of aflatoxin B1 in growing broilers. J. Appl. Anim. Res. 47(1), 135-139.
Ogbonna, C.G., Akintunde, A.O., Dupe, O.M., Arinola, A.O., Chidinma, N.-O.L., Emmanuel,A.O., Joshua, A., Taofeek, A., John, A.O., 2017. Carcass and performance characteristics of broiler chickens fed with cymbopogon citratus leaf meal as alternative to mycotoxin binder. Int. J. Agri. Sci. Res. 6(4), 18-23.
Oliveira, A., Keller, K., Deveza, M., Keller, L., Dias, E., Martini-Santos, B., Leitao, D.,Cavaglieri, L.R., Rosa, C., 2015. Effect of three different anti-mycotoxin additives on broiler chickens exposed to aflatoxin B1. Arch. Med. Vet. 47(2), 175-183.
Palupi, E., Jayanegara, A., Ploeger, A., Kahl, J., 2012. Comparison of nutritional quality between conventional and organic dairy products: a meta-analysis. J. Sci. Food.Agric. 92(14), 2774-2781.
Pappas, A.C., Tsiplakou, E., Tsitsigiannis, D.I., Georgiadou, M., Iliadi, M.K., Sotirakoglou, K., Zervas, G., 2016. The role of bentonite binders in single or concomitant mycotoxin contamination of chicken diets. Br. Poult. Sci. 57(4), 551-558.
Patil, R., Degloorkar, N., Pawar, P., 2017. Effects of ochratoxin A feeding on organ weights and gross pathological changes in broiler chicken and its amelioration with bantox®.J. Poult. Sci. Technol. 5(4), 44-51.
Raj, J., Vasiljević, M., Tassis, P., Farkaš, H., Bošnjak-Neumüller, J., Männer, K., 2021.Effects of a modified clinoptilolite zeolite on growth performance, health status and detoxification of aflatoxin B(1) and ochratoxin a in male broiler chickens. Br.Poult. Sci. 62(4), 601-610.
Rashidi, N., Khatibjoo, A., Taherpour, K., Akbari-Gharaei, M., Shirzadi, H., 2020. Effects of licorice extract, probiotic, toxin binder and poultry litter biochar on performance,immune function, blood indices and liver histopathology of broilers exposed to
aflatoxin-B1. Poult. Sci. 99(11), 5896-5906.
Riahi, I., Ramos, A.J., Raj, J., Jakovčević, Z., Farkaš, H., Vasiljević, M., Pérez-Vendrell,A.M., 2021. Effect of a mycotoxin binder (MMDA) on the growth performance,blood and carcass characteristics of broilers fed ochratoxin A and T-2 mycotoxin contaminated diets. Animals (Basel). 11(11), 3205.
Richardson, M., Garner, P., Donegan, S., 2019. Interpretation of subgroup analyses in systematic reviews: a tutorial. Clin. Epidemiology. Glob. Health. 7(2), 192-198.
Saleemi, M.K., Ashraf, K., Gul, S.T., Naseem, M.N., Sajid, M.S., Mohsin, M., He, C., Zubair,M., Khan, A., 2020. Toxicopathological effects of feeding aflatoxins B1 in broilers and its ameliosration with indigenous mycotoxin binder. Ecotoxicol. Environ. Saf.
, 109712.
Sobrane Filho, S.T., Junqueira, O.M., Laurentiz, A.C.d., Filardi, R.d.S., Rubio, M.d.S.,Duarte, K.F., Laurentiz, R.d.S.d., 2016. Effects of mycotoxin adsorbents in aflatoxin b 1-and fumonisin b 1-contaminated broiler diet on performance and blood
metabolite. Rev. Bras. Zootec. 45(5), 250-256.
Srinual, O., Moonmanee, T., Lumsangkul, C., Doan, H.V., Punyatong, M., Yachai, M.,Chaiyaso, T., Kongtong, K., Tapingkae, W., 2022. Can red yeast (Sporidiobolus pararoseus) be used as a novel feed additive for mycotoxin binders in broiler chickens?. Toxins (Basel). 14(10), 678.
Susanto, I., Rahmadani, M., Wiryawan, K.G., Laconi, E.B., Jayanegara, A., 2023. Evaluation of essential oils as additives during fermentation of feed products: a meta-analysis. Fermentation. 9(7), 583.
Weber, M., Balogh, K., Erdélyi, M., Mézes, M., 2006. Effect of T-2 toxin in combination with vitamin E, selenium and mycotoxin binder on lipid peroxide status and on the glutathione redox system in broiler chicken. J. Poult. Sci. 43(3), 222-227.
Zabiulla, I., Malathi, V., Swamy, H., Naik, J., Pineda, L., Han, Y., 2021. The efficacy of a smectite-based mycotoxin binder in reducing aflatoxin B1 toxicity on performance,health and histopathology of broiler chickens. Toxins (Basel). 13(12), 856.