Retraction Note: Immunoprotective properties of Scaphium scaphigerum fruits in cyclophosphamide-induced immunosuppressed mice targeting humoral and cell-mediated immunity https://doi.org/10.12982/VIS.2026.033

Main Article Content

Parkpoom Siriarchavatana
Naowarat Suthamnatpong
Wacharee Limpanasitthikul

Abstract

The Editors have retracted this article, Siriarchavatana et al. (2026) due to two serious of publication ethics. First, two individuals were listed as co-authors without their knowledge or consent, contradicting the Author Contributions section and breaching international authorship standards. Second, the ethical approval cited in the manuscript could not be verified, as the approval number did not exist in official records and no supporting documentation was provided. These issues—unauthorized authorship and unverifiable ethical clearance—compromise the integrity of the research and violate the journal’s ethical policies, necessitating the retraction of the article.

Article Details

How to Cite
Parkpoom Siriarchavatana, Naowarat Suthamnatpong, & Wacharee Limpanasitthikul. (2025). Retraction Note: Immunoprotective properties of Scaphium scaphigerum fruits in cyclophosphamide-induced immunosuppressed mice targeting humoral and cell-mediated immunity: https://doi.org/10.12982/VIS.2026.033. Veterinary Integrative Sciences, 24(2), 1. retrieved from https://he02.tci-thaijo.org/index.php/vis/article/view/276911
Section
Retraction Note

References

Abbas, A.K., Lichtman, A.H., Pillai, S., 2024. Basic immunology: functions and disorders of the immune system, 7th edition. Elsevier, Philadelphia, pp. 1-24.

Ai, L., Wu, J., Che, N., Wu, Y., Cui, S.W., 2012. Extraction, partial characterization and bioactivity of polysaccharides from boat-fruited sterculia seeds. Int. J. Biol. Macromol. 51(5), 815-818.

Alotiby, A., 2024. Immunology of stress: a review article. J. Clin. Med. 13(21), 6394.

Bendjeddou, D., Lalaoui, K., Satta, D., 2003. Immunostimulating activity of the hot water soluble polysaccharide extracts of Anacyclus pyrethrum, Alpinia galanga and Citrullus colocynthis. J. Ethnopharmacol. 88, 155-160.

Burana-Osot, J., Pattanapanyasat, K., Soonthornchareonnon, N., Sukapirom, K., Toida, T., 2010. Characterisation and immuno-stimulating activity of polysaccharides from Thai medicinal plants. Nat. Prod. Res. 24(15), 1403-1412.

Chen, J.M., Cao, P.R., Song, H.T., 1996. Purification and characterization of polysaccharide PP III from Sterculia lychnophora Hance. Zhongguo Zhongyao Zazhi. 21(1), 39-41. (In Chinese).

Chiavaroli, A., Brunetti, L., 2023. Food components in health promotion and disease prevention. Foods. 12(24), 4401.

Coligan, J.E., 2005. Short protocols in immunology: a compendium of methods from current protocols in immunology. John Wiley & Sons, Hoboken, pp. 1-37.

Delmonte, O.M., 2020. Immunodeficiency and disorders of immune dysregulation. Pediatr. Allergy Immunol. 31(24), 8-10.

Huang, P.H., Chiu, C.S., Lu, W.C., Hsieh, C.W., Liang, Z.C., Fan, L.L., Wang, C.C.R., Li, P.H., 2024. Antioxidant capacity, anti-inflammatory activity, and mutagenicity of Sterculia lychnophora (Pangdahai) polysaccharide. Arab. J. Chem. 17(6), 105803.

Kanlayavattanakul, M., Fungpaisalpong, K., Pumcharoen, M., Lourith, N., 2017. Preparation and efficacy assessment of malva nut polysaccharide for skin hydrating products. Ann. Pharm. Fr. 75(6), 436-445.

Kharrazian, D., 2021. Exposure to environmental toxins and autoimmune conditions. Integr. Med. (Encinitas). 20(2), 20–24.

Leung, M.Y.K., Liu, C., Koon, J.C.M., Fung, K.P., 2006. Polysaccharide biological response modifiers. Immunol. Lett. 105, 101–114.

Lommatzsch, M., van Eeden, S.F., 2020. Immune modulation in chronic respiratory diseases: the path to precision medicine. Respiration. 99(7), 548–549.

Mishra, L.C., 2004. Scientific basis for Ayurvedic therapies. CRC Press, Boca Raton, FL.

Murphy, K., Weaver, C., Janeway, C., 2017. Janeway's immunobiology, 9th edition. Garland Science, New York.

Nose, M., Terawaki, K., Oguri, K., Okihara, Y., Yoshimatsu, K., Shimomura, K., 1998. Activation of macrophages by crude polysaccharide fractions obtained from shoots of Glycyrrhiza glabra and hairy roots of Glycyrrhiza uralensis in vitro. Biol. Pharm. Bull. 21, 1110–1112.

Oppong, M.B., Cao, S., Fang, S.M., Amponsah, S.K., Donkor, P.O., Lartey, M., Adutwum, L.A., Opuni, K.F.M., Zhao, F., Feng, Q., 2024. In-vitro and in-vivo anti-inflammatory properties of extracts and isolates of Pangdahai. Phytomed. Plus. 4(2), 100533.

Oppong, M.B., Li, Y., Banahene, P.O., Fang, S.M., Qiu, F., 2018. Ethnopharmacology, phytochemistry, and pharmacology of Sterculia lychnophora Hance (Pangdahai). Chin. J. Nat. Med. 16(10), 721–731.

Palanuvej, C., Hokputsa, S., Tunsaringkarn, T., Ruangrungsi, N., 2009. In vitro glucose entrapment and alpha-glucosidase inhibition of mucilaginous substances from selected Thai medicinal plants. Sci. Pharm. 77(4), 837–850.

Pantipa, S., Wang, Q., Cui, W., Barbut, S., Jantawat, P., 2006. Malva nut gum. (Part I) Extraction and physicochemical characterization. Carbohydr. Polym. 64, 247–253.

Phlicharoenphon, W., Gritsanapan, W., Peungvicha, P., Sithisarn, P., 2017. Determination of antioxidant activity, inhibitory effect to glucose absorption and acute toxicity of Scaphium scaphigerum fruit gel powder. J. Health Res. 31(4), 289–296.

Poles, J., Karhu, E., McGill, M., McDaniel, H.R., Lewis, J.E., 2021. The effects of twenty-four nutrients and phytonutrients on immune system function and inflammation: a narrative review. J. Clin. Transl. Res. 7(3), 333–376.

Puri, A., Saxena, R.P., Sumati, Guru, P.Y., Kulshreshtha, D.K., Saxena, K.C., Dhawan, B.N., 1992. Immunostimulant activity of Picroliv, the iridoid glycoside fraction of Picrorhiza kurroa. Planta Med. 58, 528–532.

Ramamoorthy, L., Kemp, M.C., Tizard, I.R., 1996. Acemannan, a β-(1,4)-acetylated mannan, induces nitric oxide production in macrophage cell line RAW 264.7. Mol. Pharmacol. 50, 878–884.

Roth-Walter, F., Adcock, I.M., Benito-Villalvilla, C., Bianchini, R., Bjermer, L., Boyman, O., Caramori, G., Cari, L., Chung, K.F., Diamant, Z., Eguiluz-Gracia, I., Knol, E.F., Kolios, A., Levi-Schaffer, F., Nocentini, G., Palomares, O., Redegeld, F., Van Esch, B., Stellato, C., 2021. Immune modulation via T regulatory cell enhancement: Disease-modifying therapies for autoimmunity and their potential for chronic allergic and inflammatory diseases – An EAACI position paper. Allergy. 76(1), 90–113.

Sangeetha Vijayan, P., Xavier, J., Valappil, M.P., 2024. A review of immune modulators and immunotherapy in infectious diseases. Mol. Cell. Biochem. 479(8), 1937–1955.

Shirani, K., Hassani, F.V., Razavi-Azarkhiavi, K., Heidari, S., Zanjani, B.R., Karimi, G., 2015. Phytotherapy of cyclophosphamide-induced immunosuppression. Environ. Toxicol. Pharmacol. 39(3), 1262–1275.

Silva-Santana, G., Bax, J.C., Fernandes, D.C.S., Bacellar, D.T.L., Hooper, C., Dias, A., Silva, C.B., de Souza, A.M., Ramos, S., Santos, R.A., Pinto, T.R., Ramão, M.A., Mattos-Guaraldi, A.L., 2020. Clinical hematological and biochemical parameters in Swiss, BALB/c, C57BL/6 and B6D2F1 Mus musculus. Anim. Model Exp. Med. 3(4), 304–315.

Sindhu, R.K., Goyal, A., Das, J., Neha, Choden, S., Kumar, P., 2021. Immunomodulatory potential of polysaccharides derived from plants and microbes: A narrative review. Carbohydr. Polym. Technol. Appl. 2, 100044.

Trabelsi, I., Ben Slima, S., Ktari, N., Bouaziz, M., Ben Salah, R., 2021. Structure analysis and antioxidant activity of a novel polysaccharide from katan seeds. Biomed. Res. Int. 2021, 6349019.

Wang, R.F., Yang, X.W., Ma, C.M., Shang, M.Y., Liang, J.Y., Wang, X., Cai, S.Q., Shoyama, Y., 2003. Alkaloids from the seeds of Sterculia lychnophora (Pangdahai). Phytochemistry. 63(4), 475–478.

Yamada, J., Hamuro, J., Hatanaka, H., Hamabata, K., Kinoshita, S., 2007. Alleviation of seasonal allergic symptoms with superfine beta-1,3-glucan: a randomized study. J. Allergy Clin. Immunol. 119(5), 1119–1126.

Yang, X., Yang, Y., Chen, H., Xu, T., Li, C., Zhou, R., Gao, L., Han, M., He, X., Chen, Y., 2020. Extraction, isolation, immunoregulatory activity, and characterization of Alpiniae oxyphyllae fructus polysaccharides. Int. J. Biol. Macromol. 155, 927–937.

Ying, Y., Hao, W., 2023. Immunomodulatory function and anti-tumor mechanism of natural polysaccharides: a review. Front. Immunol. 14, 1170052.

Zhao, W.H., Zhao, C.Y., Gao, L.F., Feng, F.F., Gao, W., Chen, Z.L., Zhang, F., Cao, L.G., Bi, X.Y., Chen, Y., Zhu, Q.Y., Zhang, Y.X., 2008. The novel inhibitory effect of Pangdahai on fatty acid synthase. IUBMB Life. 60(3), 185–194