Achalasia
Abstract
คำว่า Achalasia ได้รับอิทธิพลจากภาษากรีก แปลว่า ไม่ยืดหยุ่น หรือ ไม่คลายตัว คำนิยามของโรค Achalasia คือ ภาวะที่หูรูดส่วนล่างของหลอดอาหารไม่สามารถคลายตัวได้ในขณะที่ไม่มี Peristalsis โดยทั่วไปผู้ป่วยส่วนใหญ่ของ Achalasia มักได้รับการรักษาเหมือนภาวะกรดไหลย้อนด้วยยาลดกรด 6-8 สัปดาห์ หลังจากนั้นถ้าอาการไม่ดีขึ้น หรือ ถ้ามีอาการกลืนลำบากที่สงสัยพยาธิสภาพที่หลอดอาหารตั้งแต่แรก จะได้รับการส่องกล้องหลอดอาหาร กระเพาะอาหาร และลำไส้เล็กส่วนต้น (Esophagogastroduodenoscopy) เพื่อหาการอุดตัน หรือรอยโรคจากการอักเสบ เมื่อไม่พบภาวะดังกล่าว ยิ่งเพิ่มความน่าจะเป็นของโรค Achalasia ยิ่งโดยเฉพาะในผู้ป่วยที่มีประวัติกลืนลำบากของเหลวร่วมด้วยแต่ต้น ในปัจจุบันการวินิจฉัยหลัก คือ High resolution esophageal manometry
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บทความที่ได้รับการตีพิมพ์เป็นลิขสิทธิ์ของกรมการแพทย์ กระทรวงสาธารณสุข
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