Co-abuse Substances in Kratom Dependent Patients


  • Lumsum Lukanapichonchat, M.D. Princess Mother National Institute on Drug Abuse Treatment
  • Viroj Verachai M.D. Princess Mother National Institute on Drug Abuse Treatment
  • Sumnao Nilaban, Ph.D. Princess Mother National Institute on Drug Abuse Treatment
  • Rossukhon Thanateerabunjong, M.Sc. Princess Mother National Institute on Drug Abuse Treatment
  • Kanchana Ratanaphan, B.Sc. Thanyarak Songkla Hospital


Kratom, Mitragynine, Drug dependence


Background: Thai teenagers like to boil kratom leaves as a base for a cocktail pattern including cough syrup, cola and other substance. These kratom decoction can produce addictive effect in addition to kratom leaves and also cause harms from other substances in the decoction.Objective: This research aimed to identify the types of drugs or substances found in kratom decoction and kratom dependent patients’ urine.Method: The samples were 69 kratom addicts who met the DSM-IV-TR and they are treated at Princess Mother National Institute on Drug Abuse Treatment (PMNIDAT), Thanyarak Songkhla Hospital, and Thanyarak Pattani Hospital. Age of samples were 18 years and older and they had willing to participate in the research. The data were collected by kratom use questionnaire which consisting of demographic data , drug use information and urine test record form. The validity kratom use questionnaire, each item has the Index of Item-Objective Congruence between 0.67-1.00. The data were analyzed by descriptive statistics such as frequency, percentage, mean and standard deviation.Result: Most kratom dependent patients put substances other than kratom leaves in kratom decoction. They mixed cola and cough syrup in kratom decoction. The top 5 substances that found in the kratom dependent patients’ urine were nicotine, mitragynine, caffeine, methamphetamine, and diphenhydramine ranging 86.95, 85.51, 62.32, 56.52 and 42.03 percent respectively.Conclusion: The substances that found in the urine were either substances that are mixed or use with kratom and contamination from food and other. Some substances may be able to cause more danger to the health of the Kratom addicts


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How to Cite

Lukanapichonchat L, Verachai V, Nilaban S, Thanateerabunjong R, Ratanaphan K. Co-abuse Substances in Kratom Dependent Patients. j dept med ser [Internet]. 2021 Nov. 30 [cited 2023 Jan. 30];46(3):96-104. Available from:



Original Article