Endotracheal Metastasis and Superior Vena Cava Obstruction from Hepatocellular Carcinoma: a Case Report


  • Sasithon Inkaew, M.D. โรงพยาบาลมะเร็งลพบุรี


Endotracheal metastasis, Hepatocellular carcinoma metastasis, Superior vena cava obstruction


Endotracheal metastasis from hepatocellular carcinoma are very rare. A 49-years-old man was admitted to the hospital with a 1-month history of cough, blood streak sputum and swelling of upper part of body. The patient had no underlying disease. Radiological findings were huge mediastinal lymphadenopathy at lower paratrachea with direct invasion to endotracheal and complete compress superior vena cava (SVC). Bronchoscopic with endotracheal lesion biopsy was done and the tissue pathology positive staining for hepatocyte paraffin 1 (Specific immunohistochemistry for HCC). Final diagnosis was advanced hepatocellular carcinomas with mediastinal lymph node and endotracheal metastasis and SVC obstruction. The patient received immediated radiation for life threatening conditions and sorafenib for specific treatment in advanced stage HCC. He died at 8 months after received sorafenib.


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How to Cite

Inkaew S. Endotracheal Metastasis and Superior Vena Cava Obstruction from Hepatocellular Carcinoma: a Case Report. j dept med ser [Internet]. 2021 Nov. 30 [cited 2023 Feb. 5];46(3):126-32. Available from: https://he02.tci-thaijo.org/index.php/JDMS/article/view/255193