Mycosis Fungoides with CD30 - positive Large Cell Transformation: Case Report
Keywords:
Mycosis fungoides, CD30 - positive Large Cell Transformation, LymphomaAbstract
Mycosis fungoides is the most common type of cutaneous T - cell lymphoma, accounting for 50% of all primary cutaneous lymphomas. It typically affects older adults, with a mean age of 55 - 60 years, and is more common in males. Although the exact cause of mycosis fungoides is unknown, various factors such as genetics, environment, and the immune system have been considered as possible contributors. Large cell transformation is a rare occurrence and is associated with a poor prognosis. This case report presented the details of a 48 - year - old female patient who had multiple ulcerated tumors that emerged on scaly erythematous plaques on her neck, trunk, groin, and extremities for a duration of 4 months. Following the performance of biopsy with H&E stains and immunohistochemical studies, the patient was diagnosed with mycosis fungoides, specifically with CD30 - positive large cell transformation.
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