Survival Rate and Factors Effecting to Survival of Colon Cancer after Surgical Treatment
Keywords:
Colon cancer, survival rate, surgical treatment, Roi Et HospitalAbstract
Objective : To investigate the factors effected to survival of colon cancer patients after surgical treatment.
Methods : A retrospective cohort studies, all variables of interested wereretrievedfrom medical records. All study subjects were new diagnosis for colon cancer at Roi Et Hospital, Roi Et Province during January 1, 2013 to December 31, 2015. All of cases were followed up the vital status until death or end of study. Data analyses were used descriptive statistics,theKaplan-Meier method to revealed disease free survival, log-rank test andCox proportional hazard models used to analyze.
Results : Of 318 colon cancer patients, most of them were female 51.39 %, with mean age 61.59+ 13.08 years. The total follow-up times were 5,861 person-months. Of 163 colon cancer were death with mortality rate was 2.78 per 100 person-months. The median survival time was 19.0 months. The cumulative 6 months, 1-, 2-, 3-, 5 years survival rate respectively were 78.33%, 65.20%, 47.36%, 40.78% and 37.09 %. The multivariable analyzed reveled cancer stage III (HR adj. = 1.63; 95% CI: 1.07-2.49), stage IV (HR adj. = 2.55; 95% CI: 1.78-3.63),cancer metastasis (HR adj. = 1.90; 95% CI: 1.29-2.75), liver metastasis(HR adj. = 3.63; 95% CI: 2.21-5.99), peritoneum metastasis (HR adj. =1.88; 95% CI: 1.05-3.36),multiple sitesmetastasis (HR adj. = 9.14; 95% CI: 3.79-22.03), regional lymph node extent (HR adj. = 2.82; 95% CI: 1.01-7.83), distant metastases (HR adj. = 8.15; 95% CI: 2.85-23.29) chemotherapy (HR adj. = 0.45; 95% CI: 0.33-0.62)andsupportive treatment (HR adj.= 2.94; 95% CI: 2.07-4.19) were factors effected to survival of patients.
Conclusion : The advanced stage of diseases, metastasis of cancer, supportive treatment and chemotherapy were factors affected to survival of coloncancer after surgical treatment.
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