Comparison of the Outcomes between St.Thomas Cardioplegia and Modified del Nido Cardioplegia in on pump Coronary Bypass Surgery
Keywords:
coronary artery bypass, del Nido cardioplegia, St. Thomas cardioplegiaAbstract
Objective: Del Nido cardioplegic solution has become an option for the treatment of on pump arrested heart surgery. This study aims to compare the outcomes of on pump arrested heart CABG procedure, using modified del Nido cardioplegia versus St.Thomas cardioplegia.
Method: A retrospective review with prospective follow-up of 102 patients in elective cases of on pump arrested heart CABG from April 2019 to April 2020. Patient’s demographic and early outcomes were analyzed.
Results: There were 68 patients underwent CABG using St.Thomas cardioplegia and 34 patients who underwent CABG using modified del Nido cardioplegia. The mean age of CABG patients using St.Thomas was 62.21+9.41 years old, and 63.12+10.38 years old for those using modified del Nido; (p-value > 0.51). There were no statistically significant differences in the two groups. There was no 30-day mortality case in both group. New neurological complications showed no statistically significant difference. Postoperative renal insufficiency was no different in either group (1.47% CABG using St.Thomas, 2.94% CABG using modified del Nido; p-value = 0.15). Prolonged intubation was not statistically different in either (0% CABG using St.Thomas, 2.94% CABG using modified del Nido; p-value = 0.61). Critical unit stay showed no difference between both groups (p-value = 0.25).
Conclusion: The on pump arrested heart CABG using modified del Nido cardioplegia solution did not have any difference in early outcome when compared to the elective, on pump arrest heart CABG using St.Thomas cardioplegia group.
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