Anti-interferon-gamma autoantibody syndrome and opportunistic skin infections: a case report and literature review
Keywords:
anti-IFN-γ autoantibodies, Opportunistic infections, Mycobacteriosis, TalaromycosisAbstract
In adulthood, patients with acquired anti-interferon-gamma (anti-IFN-) autoantibody syndrome usually suffer from recurrent and recalcitrant disseminated non-tuberculous mycobacterial (NTM) diseases with or without other opportunistic infections. We describe a case of HIV-negative, IFN- antibody positive, Thai adult who presented with disseminated Mycobacterium avium complex co-infection with cutaneous Talaromyces marneffei and Mycobacterium abscessus lymphadenitis. Anti-IFN- autoantibody syndrome should be considered in the differential diagnosis of HIVnegative adults who present with unusual, severe, or recurrent skin infections caused by NTM or other opportunistic pathogens, especially in Asian patients.
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น
