Dermatophytoma in the toenail onychomycosis

Authors

  • Lalita Matthapan DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL MAHIDOL UNIVERSITY, BANGKOK, THAILAND
  • Chanai Muanprasart DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL MAHIDOL UNIVERSITY, BANGKOK, THAILAND
  • Nuntida Prasertworonun DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL MAHIDOL UNIVERSITY, BANGKOK, THAILAND
  • Suppapat Bunyaratavej DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL MAHIDOL UNIVERSITY, BANGKOK, THAILAND
  • Penvadee Pattanaprichakul DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL MAHIDOL UNIVERSITY, BANGKOK, THAILAND
  • Charussri Leeyaphan DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL MAHIDOL UNIVERSITY, BANGKOK, THAILAND
  • Sumanas Bunyaratavej DEPARTMENT OF DERMATOLOGY, FACULTY OF MEDICINE SIRIRAJ HOSPITAL MAHIDOL UNIVERSITY, BANGKOK, THAILAND

Keywords:

onychomycosis, dermatophytoma

Abstract

Dermatophytoma is a special condition found in nails; onychomycosis. Clinical features are white, yellow patches or linear streak within the nail plates. Dermatophytoma occurs from mass of fungal ball within nail plates. Laboratory examinations reveal numerous fungal hyphae and large spores forming into fungal balls. Clinical significance of dermatophytoma is frequently resistant to conventional treatment; both topical and systemic medications. Moreover, it is considered as a poor prognostic indicator because of its fungal ball within the nail plate forms biofilm and produces extracellular polysaccharide to be resistant to several antifugal medicines. Treatment of dermatophytoma must use nail avulsion technique along with oral antifungal therapy. A single case has been reported that a patient had had tinea unguium for two years with a symptomless nail lesion and also had a wedge shape whitish streak on the right big toe. The patient received oral antifungal with no improvement. Histopathology and KOH examination revealed numerous fungal hyphae from nail clipping. Fungal culture showed Trichophyton mentagrophytes.

References

Burkhart CN, Burkhart CG, Gupta AK. Dermatophytoma : Recalcitrance to treatment because of existence of fungal biofilm. J Am Acad Dermatol 2002; 47: 629-31.

Roberts DT, Evans EG. Subungual dermatophytoma complicating dermatophyte onychomycosis. Br J Dermatol 1998;138:189-90.

Martinez-Herrera E, Moreno-Coutiño G, Fernández-Martínez RF, Finch J, Arenas R. Dermatophytoma: description of 7 cases. J Am Acad Dermatol 2012;66:1014-6.

Lee MH, Suh MK, Ha GY. A Clinico-mycological study of Onychomycosis with Dermatophytoma. Korean J Med Mycol 2013;18:21-29.

Carney C, Tosti A, Daniel R, Scher R, Rich P, DeCoster J, Elewski B. A new classification system for grading the severity of onychomysosis: Onychomycosis Severity Index. Arch Dermatol 2011; 147: 1277-82.

Scher RK, Tavakkol A, Sigurgeirsson B, et al. Onychomycosis: Diagnosis and definition of cure. J Am Acad Dermatol 2007;56:939-44.

Goodfield MJD, Evans EGV. Combined treatment with surgery and short duration oral antifungal thrapy in patients with limited dermatophyte toenail infection. J Dermatol Treat 2000;11:259-62.

Kim YS, Kim MH, Shin DH, Choi JS, Kim KG. Onychomycosis with dermatophytoma completely cured after treatment of regular subungual application of antifungal solution with systemic antifungal therapy and topical nail lacquer application. Korean J Med Mycol 2010;15:146.

Moreno-Coutiño G, Arenas R. Extraungual dermatophytoma. Rev Iberoam Micol 2009;26:165.

Downloads

Published

2026-06-09

How to Cite

Matthapan, L., Muanprasart, C., Prasertworonun, N., Bunyaratavej, S., Pattanaprichakul, P., Leeyaphan, C., & Bunyaratavej, S. (2026). Dermatophytoma in the toenail onychomycosis. Thai Journal of Dermatology, 29(2), 140–144. retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/282870

Issue

Section

Case Report