Factors associated with the normalization of blood pressure after unilateral adrenalectomy for primary hyperaldosteronism patients in Rajavithi Hospital
Objective: To determine the factors associated with the resolution of hypertension after adrenalectomy for primary hyperaldosteronism in Rajavithi Hospital.
Material and method: Records of 44 patients who underwent adrenalectomy for primary hyperaldosteronism at Rajavithi Hospital between January 2005 and April 2015 were reviewed. Patients were divided in 2 groups according to whether blood pressure was normal without antihypertensive medication at 6 months postoperatively. Clinical and biochemical data were evaluated at baseline and after the follow-up at 6 months.
Result: At the 6 month follow-up, 21 patients (47.7%) were normotensive without antihypertensive medication and 23 patients ( 52.3%) were normotensive with antihypertensive medication. Female gender (P=0.005) and duration of hypertension less than 5 years (P=0.036) were associated with normotensive without antihypertensive medication. All patients had normal serum potassium.
Conclusion: About half of the patients were normotensive without antihypertensive medication, and all the patients had normal serum potassium after adrenalectomy. Factors associated with the resolution of hypertension after adrenalectomy for primary hyperaldosteronism were female gender and duration of hypertension less than 5 years.
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