Prevalence of erectile dysfunction among obstructive sleep apnea patients
Keywords:Obstructive sleep apnea, erectile dysfunction, aging
Objective: The purpose of this study was to evaluate the prevalence of ED among OSA patients in Ramathibodi Hospital.
Material and Method: A cross-sectional study was conducted of 299 male patients who underwent diagnostic polysomnography for suspected OSA between November 2016 and April 2017. Every patient gave informed consent and completed the Thai Hospital Anxiety and Depression Scale, Epworth sleepiness scale, STOP-BANG Sleep Apnea Questionnaire, and the validated Thai version of the IIEF-5 questionnaire
before undergoing polysomnography.
Result: Two hundred ninety-nine patients who underwent sleep lab polysomnography were included in the analysis. OSA was diagnosed in 93% of the patients. The overall prevalence of ED in men diagnosed by impaired IIEF-5 score was 178 patients (59.53%). Aging, diabetes, hypertension, body mass index and sleep
lap parameters including apnea hypopnea index, respiratory disturbance index and arousal index were significantly increased in the ED group compared with the non-ED group (p<0.005). Multivariate logistic regression analysis showed aging and apnea hypopnea index were independent risk factors for ED (OR of 1.04 (95%CI 1.01-1.07) and 1.02 (95%CI 1.00-1.03), respectively).
Conclusion: These data indicate that OSA and the related intermittent hypoxia during sleep were associated with impaired erectile function. OSA can be used as a risk factor for ED.
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