Renal function after donor nephrectomy at a tertiary medical center in Southern Thailand

Authors

  • Apiwich Anukoolphaiboon Division of Urology, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand
  • Virote Chalieopanyarwong Division of Urology, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand
  • Worapat Attawettayanon Division of Urology, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand
  • Komsan Leetanaporn Division of Urology, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand
  • Monthira Tanthanuch Division of Urology, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand
  • Choosak Pripatnanont Division of Urology, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand

Keywords:

Kidney transplantation, donor nephrectomy, renal function

Abstract

Objective: The aim of this study was to assess long-term renal function after living donor nephrectomy and determine the optimal follow-up period.
Material and Method: A retrospective review of living donor kidney transplantation (LDKT) patients who underwent open donor nephrectomy. Clinical chart review was performed. Kidney function was measured before and after surgery. We assessed donor kidney function using the estimated Glomerular filtration rate (eGFR) through the Cockcroft and Gault formula. The evaluation of kidney function after surgery
was performed at 1 week, 1 month, 3 months, 6 months, and 12 months. Rate of renal function decline was analyzed and compared with the baseline.
Result: A total of 50 kidney donor patients were identified; the mean age of kidney donors was 39.18 (11.37) years old. The mean of eGFR before surgery was 92.4 (26.0) ml/min/1.73 m2. After surgery eGFR at 1 week, 1 month, 3 months, 6 months and 12 months was 66.8 (18.3) ml/min/1.73 m2, 66.8 (21.0) ml/min/
1.73 m2, 65.8 (18.6) ml/min/1.73 m2, 69.4 (17.4) ml/min/1.73 m2, 70.0(16.0) ml/min/1.73 m2 respectively. Kidney function was reduced and returned to a new baseline at 6 months after surgery. The overall new baseline eGFR decreased 22.6% from eGFR at pre-donation.
Conclusion: Renal function declined after open donor nephrectomy. Change in renal function is not associated with gender. New baseline of eGFR will occur at 6 months after surgery.

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References

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Published

2020-06-29

How to Cite

Anukoolphaiboon, A., Chalieopanyarwong, V., Attawettayanon, W., Leetanaporn, K., Tanthanuch, M., & Pripatnanont, C. (2020). Renal function after donor nephrectomy at a tertiary medical center in Southern Thailand. Insight Urology, 41(1), 25–29. Retrieved from https://he02.tci-thaijo.org/index.php/TJU/article/view/242824

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Original article