Nocturia and effect on the quality of life. A study at Ramathibodi Hospital

Authors

  • Potchara Kanammit Division of Urology, Department of Surgery, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • Threechada Boonchan Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • Pokket Sirisreetreerux Division of Urology, Department of Surgery, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • Wit Viseshsindh Division of Urology, Department of Surgery, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • Wachira Kochakarn Division of Urology, Department of Surgery, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

DOI:

https://doi.org/10.52786/isu.a.37

Keywords:

Nocturia, quality of life, lower urinary tract symptoms, impact, sleep quality

Abstract

Objective: To investigate the impact and the incidence of nocturia on the quality of life of patients in Ramathibodi Hospital.

Materials and Methods: This study was a hospital-based cross-sectional study to measure the QoL of nocturia patients using a Nocturia Quality-of-Life questionnaire (N-QoL). Cronbach’s alpha coefficient was used to explore internal consistency. Pearson’s correlation coefficient (r) was used to determine the strength of the relationship between the scores for each item. Uni- and Multivariate analyses were used to explore the significant parameters.

Results: One hundred and fifty-five nocturia patient were included in the study analysis. Most of the questionnaire respondents were male (80.65%) and the vast majority had at least 1 underlying disease requiring long-term follow-up by a physician (86.45%) with a median urination of 3 times per night and a 3 hour median first urination after retiring to bed. From our study questionnaire, most patients responded that they had moderate to good quality of life with a minor inconvenience from nocturia, requiring them to nap during the day on some days. An increasing frequency of urination per night and a first urination of less than 2 hours after retiring is significantly related to low levels of energy the next day, sleep deprivation, worry over treatment options, overall inconvenience and a reduction in quality of life.

Conclusion: Our study demonstrated nocturia patients experience a significant reduction in quality of life, and a decrease in quality of sleep. The incidence of urination in the night and the timing of the first urination after bed had more impact on overall quality of life.

References

van Kerrebroeck P, Abrams P, Chaikin D, Donovan J, Fonda D, Jackson S, et al. The standardisation of terminology in nocturia: report from the Standard- isation Sub-committee of the International Continence Society. Neurourol Urodyn 2002;21:179-83.

Fitzgerald MP, Litman HJ, Link CL, McKinlay JB. The association of nocturia with cardiac disease, diabetes, body mass index, age and diuretic use: results from the BACH survey. J Urol 2007;177:1385-9.

Swatesutipun V. Diagnosis and management of nocturia. Thammasat Med J 2017;17:390-401.

Bosch JL, Weiss JP. The prevalence and causes of nocturia. J Urol 2010;184:440-6.

Manonai J, Chittacharoen A, Sarit-apirak S, Udomsubpayakul U, Adchara A, Theppisai U. Lower Urinary Tract Symptoms in Thai Women Attending the Menopause Clinic: Prevalence and Associated Factors. J Med Assoc Thai 2004;87:1265-9.

Zeitzer JM, Bliwise DL, Hernandez B, Friedman L, Yesavage JA. Nocturia compounds nocturnal wakefulness in older individuals with insomnia. J Clin Sleep Med 2013;9:259-62.

Parsons JK, Mougey J, Lambert L, Wilt TJ, Fink HA, Garzotto M, et al. Lower urinary tract symptoms increase the risk of falls in older men. BJU Int 2009;104:63-8.

Kupelian V, Wei JT, O’Leary MP, Norgaard JP, Rosen RC, McKinlay JB. Nocturia and quality of life: results from the Boston area community health survey. Eur Urol 2012;61:78-84.

Kupelian V, Fitzgerald MP, Kaplan SA, Norgaard JP, Chiu GR, Rosen RC. Association of nocturia and mortality: results from the Third National Health and Nutrition Examination Survey. J Urol 2011;185:571-7.

Sirikulchayanonta S, Permpongkosol S. The Etiologic Classification of Nocturia among 133 Thai Patients in a Tertiary Teaching Hospital. Open J Urol 2013;3:32-6.

Abraham L, Hareendran A, Mills IW, Martin ML, Abrams P, Drake MJ, et al. Development and validation of a quality-of-life measure for men with nocturia. Urology 2004;63:481-6.

Guyatt GH, Feeny DH, Patrick DL. Measuring health-related quality of life. Ann Intern Med 1993;118:622-9.

Mukaka MM. Statistics corner: A guide to appropriate use of correlation coefficient in medical research. Malawi Med J 2012;24:69-71.

Oelke M, De Wachter S, Drake MJ, Giannantoni A, Kirby M, Orme S, et al. A practical approach to the management of nocturia. Int J Clin Pract 2017;71:e13027.

Choi EPH, Wan EYF, Kwok JYY, Chin WY, Lam CLK. The mediating role of sleep quality in the association between nocturia and health-related quality of life. Health Qual Life Outcomes 2019;17:181.

Azuero J, Santander J, Trujillo CG, Caicedo JI, Zuluaga L, Becerra AM, et al. Potential associations of adult nocturia. Results from a national prevalence study. Neurourol Urodyn 2021;40:819-28.

Bozkurt O, Irer B, Kizilay F, Sen V, Cinar O, Ongun S, et al. Mechanisms and grading of nocturia: Results from a multicentre prospective study. Int J Clin Pract 2020;75:e13722.

Pesonen JS, Cartwright R, Vernooij RWM, Aoki Y, Agarwal A, Mangera A, et al. The Impact of Nocturia on Mortality: A Systematic Review and Meta-Analysis. J Urol 2020;203:486-95.

Torimoto K, Uchimura N, Roitmann E, Marumoto M, Hirakata T, Burtea T. A large survey of nocturia related to sleep quality and daytime quality of life in a young Japanese population: NOCTURNE study. Neurourol Urodyn 2021;40:340-7.

Zeng VY, Milligan G, Piercy J, Anderson P, Andersson FL. Impact of nocturia on patients’ health-relat- ed quality of life and healthcare resource utilisation compared with OAB and BPH: Results from an observational survey in European and American patients. Int J Clin Pract 2019;e13408.

Theerawirojana M, Wongwattanasatien N. Evalua- tion of lower urinary tract symptoms and clinical outcome after renal transplantation at Rajavithi Hospital. Thai J Urol 2013;34:13-9.

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Published

2021-11-30

How to Cite

Kanammit, P., Boonchan, T., Sirisreetreerux, P., Viseshsindh, W., & Kochakarn, W. (2021). Nocturia and effect on the quality of life. A study at Ramathibodi Hospital. Insight Urology, 42(2), 144–153. https://doi.org/10.52786/isu.a.37

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Original article