Outcomes of Transrectal Ultrasound- Guided Biopsy of Prostate using Chulalongkorn Regimen
Keywords:
Outcomes, Transrectal Ultrasound- Guided Biopsy of Prostate, Chulalongkorn RegimenAbstract
This study was designed to assess the complications of transrectal ultrasound-guided (TRUS) biopsy of prostate using Chulalongkorn Regimen. 225 men with suspicion of prostate cancer were under- went 239 TRUS biopsies of prostate between January 2006 and January 2007. All patients received ciprofloxacin 500-1,000 mg or ofloxacin 200 mg, one to three hours before procedures and continuation for 5 days after biopsy. The overall complication rate was 7.5% (infectious complication 2.9%, persistent hematuria 2.1%, urinary retention 1.7%, and hematospermia 0.8%). There was no mortality in this study. Ciprofloxacin and ofloxacin are the effective prophylactic antibiotics for TRUS biopsy of prostate.
References
Aron M, Rajeef TP, Gupta NP. Antibiotic prophylaxis for transrectal needle biopsy of the prostate: a randomized controlled study. BJU Int 2000; 85(6): 682-5.
Cormio L, Berardi B, Callea A, et al. Antimicrobial prophylaxis for transrectal prostatic biopsy: a prospective study of ciprofloxacin vs piperacillin/tazobactam. BJU Int 2002; 90: 700-2.
Noguchi M, Matsuoka K, Koga H, Kanetake H, Nakagawa M, Naito S. A questionnaire survey of patient preparation and techniques for prostate biopsy among urologists in the Kyushu and Okinawa regions of Japan. Int J Clin Oncol 2006; 11: 390-5.
Schaeffer AJ. Infection of the urinary tract. In: Walsh PC, Retik AB, Vaughan ED Jr, Wein AJ, editors. Campbellûs Urology. 8th ed. Philadelphia: WB Saunders; 2002. p. 515-602.
Carry JM, Korman HJ. Transrectal ultrasound guided biopsy of the prostate: do enemas decrease clinically significant complica- tion? J Urol 2001; 166: 82-5.
Kapoor DA, Klimberg IW, Malek GH, et al. Single-dose oral ciprofloxacin versus placebo for prophylaxis during transrectal prostate biopsy. Urology 1998; 52: 552-8.
Jeon SS, Woo SH, Hyun JH, Choi HY, Chai SE. Bisacodyl rectal preparation can decrease infectious complications of transrectal ultrasound-guided prostate biopsy. Urology 2003; 62: 461-6.
Wammack R, Djavan B, Remzi M, Susani M, Marberger M. Morbidity of transrectal ultrasound-guided prostate needle biopsy in patients receiving immunosuppression. Urology 2001; 58: 1004-7.
Griffith BC, Morey AF, Ali-Khan MM, Canby-Hagino E, Foley JP, Rozanski TA. Single dose levofloxacin prophylaxis for prostate biopsy in patients at low risk. J Urol 2002; 168: 1021-3.
