Risk of Prostate Cancer Detection in Thai Men with Abnormal PSA Testing
Keywords:
Risk, Prostate Cancer, Detection, Abnormal PSA TestingAbstract
This study determined the risks of prostate cancer detection in Thai men by PSA level. The study included 662 Thai men with abnormal PSA or abnormal DRE or both and their prostate glands were biopsied by transrectal ultrasound (TRUSBx) from 1999 to 2003. The risk of positive biopsy according to the PSA levels of 0-4 ng/ml, 4.1-10.0 ng/ml, 10.1-20.0 ng/ml, 20.1-50 ng/ml, 50.1-100 ng/ml and more than 100 ng/ml were 6.5%, 12.5%, 21.2%, 38.9%, 60% and 96.4%, respectively. Since high detection rate of prostate cancer was correlated with high PSA but pros- tate cancer may present in Thai men with normal PSA, thus PSA testing alone is not a best test for diagnosis of prostate cancer. If abnormal DRE or abnormal PSA or both was detected in a patient, TRUSBx should be performed and interpretation of the risk for prostate cancer for Thai men should use data in Thai men.
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