Erectile function in end-stage renal disease before and after renal transplantation
DOI:
https://doi.org/10.52786/isu.a.59Keywords:
Erectile dysfunction, renal transplantation, International Index of Erectile Function, IIEF-5, testosterone, end stage renal diseaseAbstract
Objective: Erectile dysfunction (ED) can be defined as the inability to achieve or maintain an erection of sufficient firmness for vaginal penetration and sexual satisfaction. Details pertaining to erectile function among end-stage renal disease (ESRD) and renal transplant patients remains controversial. The objective of this study was to evaluate erectile function before and after renal transplantation in all male renal transplant recipients in Chiang Mai University Hospital.
Materials and Methods: This study included 35 patients with ESRD who underwent renal transplantation at Chiang Mai University Hospital. Erectile function in these patients was assessed using the 5-item Thai version of the International Index of Erectile Function (IIEF-5) and serum testosterone levels were measured before and 3, 6 and 12 months after renal transplantation. After the transplant, changes in IIEF-5 scores were analyzed based on the duration of dialysis.
Results: Out of 35 patients, 6 (17.1%) patients had severe ED, 12 (34.2%) patients were scored as moderate, 8 (22.8%) as mild to moderate, 7 (20%) as mild, and 2 (5.7%) patients had no ED in the period before renal transplantation. Twelve months after renal transplantation 2 (6.2%) patients had severe ED, 2 (6.2%) patients had moderate ED, 5 (15.6%) patients had mild to moderate ED, 7 (21.8%) patients had mild ED and 16 (50%) had no ED. There was a significant difference between before- and after-transplant IIEF-5 scores (p < 0.05) in patients who had been on dialysis for more than six months. Serum levels of testosterone had increased significantly at the 12 month check following transplantation (3.25 ± 1.54 vs. 5.76 ± 1.73 ng/ml, p < 0.001).
Conclusion: After successful renal transplantation, many patients showed a significant improvement in erectile function score, especially in those with a history of longer duration of dialysis. Increase in testosterone levels can contribute to the improvement of ED
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