Accuracy of detecting recurrent rate of NMIBC by NBI and WLC: the prospective study
DOI:
https://doi.org/10.52786/isu.a.97Keywords:
Narrow-band imaging cystoscopy, white light csytoscopy, non-muscle invasive bladder cancer, transurethral resection of bladder tumorsAbstract
Objective: The aim of this study was to investigate the accuracy of narrow-band imaging cystoscopy (NBI) in cases of recurrent non-muscle invasive bladder cancer (NMIBC) compared to standard white light cystoscopy (WLC).
Materials and Methods: All NMIBC patients at Rajavithi Hospital, Thailand were enrolled onto this single-center prospective cohort study. The patients were diagnosed by transurethral resection of bladder tumor (TURBT) then underwent both WLC and NBI carried out by the same two urologists. Cold cup biopsy was performed for all visible lesions.
Results: A total of 67 NMIBC patients were enrolled onto the study. The male to female ratio was 3.5 : 1, the mean age was 69.2±10.7 years, and stage Ta and T1 were 56.7% and 43.3% respectively. Papillary urothelial neoplasm of low malignant potential (PUNLMP), low and high grade were 3.0%, 37.3%, and 59.7% respectively. The NBI significantly improved the detection rate of NMIBC and carcinoma in situ (CIS) in comparison to standard WLC (100.0% versus 80.0% and 100.0% versus 0.0% respectively). Also, NBI cystoscopy resulted in significantly superior detection rates for CIS and overall tumors. However, specificity was lower (84.0% versus 93.0%) and the false positive rates of NBI were higher than WLC (15.7% versus 7.01%).
Conclusion: NBI cystoscopy is an alternative procedure for patients with recurrent NMIBC, with significant levels of improvement regarding tumor detection. This technique may lead to better outcomes from early treatment.
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