Overall Survival and Prognostic Factor for Breast Cancer in Nopparat Rajathanee Hospital
Keywords:
Breast cancer, Five-year survival, Prognostic factorAbstract
Background: Breast cancer is the most common cancer in Thai women. Although, there are more effective treatment methods, the mortality rate is still high. The study of prognostic factors enables the development of appropriate treatment, screening plans and finally increases the survival rate of breast cancer.
Objective: The purpose of this study was to examine the 5-year survival rate and prognostic factors of breast cancer patients at Nopparat Rajathanee Hospital.
Material and methods: This study was a retrospective study. The study included 325 new female breast cancer patients diagnosed during the period January 2009 to December 2016 who got definite treatment in Nopparat Rajathanee Hospital.
Result: The patient’s mean age was 59.4±11.1 years. 307 patients(94.5%) received an operation(mastectomy).The most common histological type was invasive ductal carcinoma (89.5%). The overall five-year survival was 88.6%. The five-year overall survival rate in stages 0, I, II, III, and IV were 100%, 100%, 93.2%, 80.7%, and 33.3% respectively. The triple negative subtype, recurrence, and late stage 3-4 have negatively affected patient survival rate. Adjuvant therapy has a protective effect on patient survival rate.
Conclusions: The overall five-year survival rate was 88.6%. The triple negative subtype, the late stage(node involvement), metastasis of disease, and recurrence of the disease negatively affected patient survival rates.
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วรางคณา จันทรสุข, ดุสิต สุจิรารัตน์, อรุณรักษ์ คูเปอร์ มีใย, อาคม ชัยวีระวัฒนะ. การศึกษาปัจจัยในการพยากรณ์ และการรอดชีพของผู้ป่วยมะเร็งเต้านม สถาบันมะเร็ง แห่งชาติใน:รัตติยากร วิมลศิริ, พาณิภัค พระชัย, ดิลกรัตน์ โคตรสุมาตย์, อภิเชษฐ์ บุญจวง, ปัทมาสมพงษ์, พรนภา โยธาฤทธิ์และคณะ, บรรณาธิการ. เอกสารรวมบทคัดย่อ การประชุมวิชาการเสนอผลงานวิจัยระดับบัณฑิตศึกษา ครังที่ 15; 28 มีนาคม 2557; ณ มหาวิทยาลัยขอนแก่น. ขอนแก่น: บัณฑิตวิทยาลัย มหาวิทยาลัยขอนแก่น; 2557. หน้า 1807-1813.
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