Analysis of Bacterial pathogens and Multidrug-Resistant and Extensively Drug-resistant patterns from Blood Cultures in Results in Emergency Department Patients at Samutsakhon Hospital
Keywords:
Bacteria, Bloodstream infection, Multidrug-resistant bacteriaAbstract
Background: Sepsis is a critical medical emergency with increasing incidence and severity, particularly due to the growing prevalence of antimicrobial-resistant pathogens. Accurate data on causative microorganisms and resistance patterns are essential to guide appropriate early treatment decisions.
Objective: To analyze the types of bacterial pathogens and patterns of multidrug-resistant (MDR) and extensively drug-resistant (XDR) organisms from blood cultures in patients admitted to the emergency department of a provincial hospital.
Methods: This descriptive study included patients aged over 18 years who were admitted to the emergency department of a provincial hospital between September 1, 2023, and August 31, 2024. A total of 426 cases were reviewed. Data were collected on age, sex, bacterial species identified, and 324 cases for analysis of antimicrobial resistance profiles.
Results: The mean age of patients was 67 ± 15.9 years, with 50.70% being male. The most common bacterial pathogens identified were Gram-negative bacilli/coccobacilli (50.70%). The most frequently isolated organism was E. coli (27.00%), followed by S. hominis (10.80%) and K. pneumoniae (9.86%). ESKAPE pathogens detected included K. pneumoniae, S. aureus, A. baumannii, P. aeruginosa, and E. faecium. Among 324 cases with complete antimicrobial data, the prevalence of MDR/XDR organisms was 31.48%, most notably E. coli, K. pneumoniae, A. baumannii, and P. aeruginosa.
Conclusion: Sepsis cases in the Emergency Department showed a high rate of drug-resistant infections, particularly among Gram-negative ESKAPE pathogens. These findings highlight the urgent need for an appropriate antibiotic stewardship strategy to reduce the severity of antimicrobial-resistant pathogens and transmission of antimicrobial-resistant pathogens.
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