Comparison of Pupil Dilation between Adrenaline 0.6 microgram/ml and 1.0 microgram/ml in Balance Salt Solution Intracamerally during Phacoemulsification
Abstract
Abstract
Objective: To study pupillary dilation in patients using intracameral Adrenaline 0.6 microgram/ml in balance
salt solution (BSS) (group A) and adrenaline 1.0 microgram/ml (group B) during phacoemulsification.
Study design: Prospective randomized clinical study.
Method: Study participants are patients underwent phacoemulsification in Trang Hospital by a single
surgeon. The patients’ age, sex, underlying diseases, cataract type, IOL power, pre- and post-operative
visual acuity were collected. The patients were randomized into group A (using adrenaline 0.6 microgram/
ml) And group B (using adrenaline 1.0 microgram/ml). Pupil diameters of each patient were measured
using caliper under operating microscope 3 times, first at the beginning of the surgery, second at one
minute after intracameral adrenaline in BSS irrigation, and third after viscoelastic injection. Standard
phacoemulsification was performed and the patients were managed routinely after the operation.
Results: There are 65 patients participated in the study. The average age was 67.8 ± 10.9 years. Fifty four
percent of the patients were male. The average pre-adrenaline injection pupil diameters were 5.6 ± 0.8
mm in group A and 6.0 ± 0.9 mm in group B. The average pupil diameters after adrenaline application
were 6.6 ± 1.0 mm in group A And 7.1 ± 0.8 mm in group B. The average pupil diameters after viscoelastic
injection were 7.3 ± 0.8 mm in group A and 7.7 ± 0.8 mm In group B. The mean visual acuity at one-week
post-operation were 20/40 in group A and 20/30 in group B. One person in group A had A post-operative
complication (increased intraocular pressure) which responded well after treatment.
Conclusion: Both concentration of adrenaline in BSS applied Intracamerally can increase pupillary dilation
and are useful in Phacoemulsification.
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