The Association of Obesity and Severity of Acute Pancreatitis in Uttaradit Hospital

Authors

  • Kunchan Chayangkoontanat Medical Education Center, Uttaradit Hospital
  • Chatkul Lueamsaisat Medical Education Center, Uttaradit Hospital
  • Teetut Khamsuwan Medical Education Center, Uttaradit Hospital
  • Hanwadee Suphitchayasakul Medical Education Center, Uttaradit Hospital

DOI:

https://doi.org/10.1016/hscr.v37i2.259630

Keywords:

Obesity, Severity of Acute pancreatitis, Acute pancreatitis, Body mass index

Abstract

Objective: To study the relationship between obesity and the severity of acute pancreatitis.

Method: Studying 194 Acute severe patients in Uttaradit hospital from July 13th, 2019 - July 13th, 2022. There were 97 patients who had obesity and 97 Patients who had non-obesity. Collecting data from ICD-10 (K850- K859) medical records divided into 2 groups. Classification of severity of acute pancreatitis by Revised Atlanta Classification. All data were analyzed by descriptive and analytics study.

Result: Acute pancreatitis patients with obesity have 0.78 times risk of increasing severity of acute pancreatitis with not statistically significant (OR=0.78, 95% CI=0.41-1.50, p=0.456)

Conclusion: There is no relationship between obesity and the severity of acute pancreatitis. Because the severity of acute pancreatitis does not depend on obesity alone, but it depends on a variety of factors. However, obesity poses a risk of developing many health problems. Disease progression and prevention should be monitored to improve quality of life in the future.

Keywords: Obesity, Acute pancreatitis, Body mass index

References

Phuttapitakphong C. Management of Acute Pancreatitis. 2559 Jun;69(2):89–99.

Phuttapitakphong C. Management of Chronic Pancreatitis. 2561 Jun;71(2):141–9.

Gapp J, Chandra S. Acute Pancreatitis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 [cited 2022 Jul 14]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK482468/

Leppäniemi A, Tolonen M, Tarasconi A, Segovia-Lohse H, Gamberini E, Kirkpatrick AW, et al. 2019 WSES guidelines for the management of severe acute pancreatitis. World J Emerg Surg. 2019;14:27.

Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, et al. Classification of acute pancreatitis--2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013 Jan;62(1):102–11.

Zhou H, Mei X, He X, Lan T, Guo S. Severity stratification and prognostic prediction of patients with acute pancreatitis at early phase: A retrospective study. Medicine (Baltimore). 2019 Apr;98(16):e15275.

Panuganti KK, Nguyen M, Kshirsagar RK. Obesity. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 [cited 2022 Jul 13]. Available from: http://www.ncbi.nlm.nih.gov /books/NBK459357/

Overweight and obesity. [Internet]. Thai Health Promotion Foundation. 2555. Available from: https://www.thaihealth.or.th/Content/20399.html

Sakboonyarat B, Pornpongsawad C, Sangkool T, Phanmanas C, Kesonphaet N, Tangthongtawi N, et al. Trends, prevalence and associated factors of obesity among adults in a rural community in Thailand: serial cross-sectional surveys, 2012 and 2018. BMC Public Health. 2020 Jun 3;20(1):850.

Saisho Y, Butler AE, Meier JJ, Monchamp T, Allen-Auerbach M, Rizza RA, et al. Pancreas volumes in humans from birth to age one hundred taking into account sex, obesity, and presence of type-2 diabetes. Clin Anat. 2007 Nov;20(8):933–42.

Khatua B, El-Kurdi B, Singh VP. Obesity and pancreatitis. Curr Opin Gastroenterol. 2017 Sep;33(5): 374–82.

Dobszai D, Mátrai P, Gyöngyi Z, Csupor D, Bajor J, Eross B, et al. Body-mass index correlates with severity and mortality in acute pancreatitis: A meta-analysis. World J Gastroenterol. 2019 Feb 14;25(6):729–43.

Kim DB, Chung WC, Lee JM, Lee KM, Oh JH, Jeon EJ. Analysis of Factors Associated with the Severity of Acute Pancreatitis according to Etiology. Gastroenterol Res Pract. 2017; 2017:1219464.

Jitnarin N, Kosulwat V, Rojroongwasinkul N, Boonpraderm A, Haddock CK, Poston WSC. Prevalence of overweight and obesity in Thai population: results of the National Thai Food Consumption Survey. Eat Weight Disord. 2011 Dec;16(4):e242-249.

Khanna AK, Meher S, Prakash S, Tiwary SK, Singh U, Srivastava A, et al. Comparison of Ranson, Glasgow, MOSS, SIRS, BISAP, APACHE-II, CTSI Scores, IL-6, CRP, and Procalcitonin in Predicting Severity, Organ Failure, Pancreatic Necrosis, and Mortality in Acute Pancreatitis. HPB Surg. 2013;2013:367581.

İnce AT, Seven G, Koçhan K, Kiremitçi S, Yıldız K, Şentürk H. The course of acute pancreatitis inpatients with different BMI groups. Pancreatology. 2022 Apr;22(3):348–55.

Párniczky A, Kui B, Szentesi A, Balázs A, Szucs Á, Mosztbacher D, et al. Prospective, Multicentre, Nationwide Clinical Data from 600 Cases of Acute Pancreatitis. PLoS One. 2016;11(10):e0165309.

Bota S, Sporea I, Sirli R, Popescu A, Strain M, Focsa M, et al. Predictive factors for severe evolution in acute pancreatitis and a new score for predicting a severe outcome. Ann Gastroenterol. 2013;26(2):156–62.

Guiraudou M, Varlet-Marie E, Raynaud de Mauverger E, Brun JF. Obesity-related increase in whole blood viscosity includes different profiles according to fat localization. Clin Hemorheol Microcirc. 2013;55(1):63–73.

Purdy JC, Shatzel JJ. The hematologic consequences of obesity. Eur J Haematol. 2021 Mar;106(3):306–319

Kebkalo A, Tkachuk O, Reyti A. Features of the course of acute pancreatitis in patients with obesity. Pol Przegl Chir. 2019 Sep 11;91(6):28–34.

Szentesi A, Párniczky A, Vincze Á, Bajor J, Gódi S, Sarlós P, et al. Multiple Hits in Acute Pancreatitis:Components of Metabolic Syndrome Synergize Each Other’s Deteriorating Effects. Front Physiol. 2019;10:1202.

Lee DW, Cho CM. Predicting Severity of Acute Pancreatitis. Medicina (Kaunas). 2022 Jun 11;58(6):787.

Downloads

Published

2022-12-30

How to Cite

1.
Chayangkoontanat K, Lueamsaisat C, Khamsuwan T, Suphitchayasakul H. The Association of Obesity and Severity of Acute Pancreatitis in Uttaradit Hospital. HSCR [Internet]. 2022 Dec. 30 [cited 2024 Dec. 27];37(2):13-24. Available from: https://he02.tci-thaijo.org/index.php/hscr/article/view/259630

Issue

Section

Original Articles (นิพนธ์ต้นฉบับ)
Share |