The Prevalence of Pathogen and Clinical Outcomes of Infective Endocarditis in Uttaradit Hospital


  • Phasakorn Putchagarn Department of Internal Medicine Uttaradit hospital



Infective endocarditis, Uttaradit, Streptococcus suis


Background: Infective endocarditis (IE) is a severe cardiac infection that affects individuals with multiple cardiac valve conditions. In Thailand, the overall in-hospital mortality rate is high, and people in Uttaradit province are at risk of exposure to Streptococcus Suis due to certain behaviors and occupations. However, data on the prevalence of pathogens and clinical outcomes, especially Streptococcus Suis, at Uttaradit hospital are limited.

Methods: This retrospective cohort study collected data from left-sided, native-valve endocarditis patients who underwent echocardiography at Uttaradit Hospital between January 2017 and December 2022. Patients were stratified by the organism, and the primary outcome was in-hospital death. The secondary outcome was death at 6 months of follow-up.

Results: Of the 69 patients with IE included in the study, Streptococcus Suis was the most prevalent pathogen 17 patients (24.6%). In-hospital mortality and any death at 6 months were 24.6% and 33.3%, respectively. The Streptococcus Suis group had a numerically higher in-hospital mortality than the non-Streptococcus Suis group (29.4% vs. 23.1%), but the difference was not significant (HR=1.35, CI 0.48-3.84, p=0.569). At 6 months, all-cause mortality in both groups was 47.1% and 28.8%, respectively (HR=1.64, CI 0.74-4.10, p=0.207). The study found that in univariate analysis, T2DM, Euroscore II, and alteration of consciousness were all associated with 6-month mortality in IE patients. However, in multivariate analysis, only alteration of consciousness remained a significant predictor of mortality, with a hazard ratio of 4.96, 95% CI 1.88-13.08, and p=0.001.

Conclusion: The overall in-hospital mortality and 6-month mortality rate of IE at Uttaradit hospital were high. Streptococcus Suis was prevalent, but not significantly associated with higher mortality compared to other organisms.

Keywords: Infective endocarditis, Uttaradit, mortality, Streptococcus suis


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How to Cite

Putchagarn P. The Prevalence of Pathogen and Clinical Outcomes of Infective Endocarditis in Uttaradit Hospital. HSCR [Internet]. 2023 Dec. 29 [cited 2024 Apr. 21];38(2):25-34. Available from:



Original Articles (นิพนธ์ต้นฉบับ)
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