ความสอดคล้องของการวินิจฉัยก้อนต่อมไทรอยด์ด้วยคลื่นเสียงความถี่สูงในระบบ ACR TI-RADS กับผลตรวจชิ้นเนื้อทางพยาธิวิทยาจากการผ่าตัดต่อมไทรอยด์ ในโรงพยาบาลอุตรดิตถ์

ผู้แต่ง

  • สุภาวรรณ กีรติเรืองรอง กลุ่มงาน โสต ศอ นาสิกวิทยา โรงพยาบาลอุตรดิตถ์

DOI:

https://doi.org/10.1016/hscr.v41i1.280417

คำสำคัญ:

ความสามารถในการวินิจฉัย, การตรวจด้วยคลื่นเสียงความถี่สูง, ACR TI-RADS, ความไว, การตรวจคัดกรอง, ก้อนต่อม ไทรอยด์, มะเร็งต่อมไทรอยด์

บทคัดย่อ

ABSTRACT
Objective: To evaluate the diagnostic performance of thyroid nodule assessment by ultrasound using the ACR TI-RADS reporting system in predicting thyroid malignancy, compared with histopathological results from thyroidectomy specimens in Uttaradit Hospital.
Methods: This study is a retrospective descriptive study of patients with thyroid nodules who underwent ultrasound examination reported using the ACR TI-RADS system and subsequently received thyroid surgery in Uttaradit Hospital between October 1, 2021 and October 1, 2025.
Results: There were a total of 95 patients included in the study. Of these, 88 were female (92.6%). The mean age was 50 years old (50.42 ± 12.73). The diagnostic performance of ultrasound evaluation using the ACR TI-RADS system for thyroid nodules, compared with histopathological results from thyroidectomy specimens, showed sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio, negative likelihood ratio, and accuracy of 80.6 (95% CI=64.0 - 91.8), 41.3 (95% CI=31.1
- 52.1), 34.9 (95% CI=24.8 - 46.2), 84.4 (95% CI=70.5 - 93.5), 1.37 (95% CI=1.09 - 1.74), 0.47 (95% CI=0.23 - 0.96), 52.34 (95% CI=43.34 - 61.24), respectively.
Conclusions: This study demonstrated that ultrasound evaluation and reporting using the ACR TI-RADS classification system in Uttaradit Hospital are useful for the screening and risk strati􀏐ication of thyroid nodules. The high sensitivity and negative predictive value observed in this study suggest that ACR TI-RADS may help reduce missed diagnoses of thyroid malignancy and assist in identifying patients who require further diagnostic evaluation. However, the relatively low speci􀏐icity and positive predictive value indicate that reliance on ultrasound 􀏐indings alone for surgical decision-making may result in unnecessary thyroid surgeries. Therefore, ultrasound assessment should be interpreted in conjunction with clinical findings, fine-needle aspiration (FNA) cytology results, and other relevant risk factors when planning
patient management and treatment.

เอกสารอ้างอิง

Mu C, Ming X, Tian Y, Liu Y, Yao M, Ni Y, et al. Mapping global epidemiology of thyroid nodules among general population: a systematic review and meta-analysis. Front Oncol. 2022;12:1029926. doi:10.3389/fonc.2022.1029926.

Lyu Z, Zhang Y, Sheng C, Huang Y, Zhang Q, Chen K. Global burden of thyroid cancer in 2022: Incidence and mortality estimates from GLOBOCAN. Chin Med J (Engl). 2024 Nov 5;137(21):2567-2576. doi:10.1097/CM9.0000000000003284. Epub 2024 Sep 12. PMID: 39261986; PMCID: PMC11557048.

Haugen BR, Alexander EK, Bible KC, et al. 2015 American thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: The American thyroid association guidelines task force on thyroid nodules and differentiated

thyroid cancer. Thyroid 2016; 26:1-133.

Tessler FN, Middleton WD, Grant EG, et al. ACR Thyroid Imaging, Reporting and Data System (TI-RADS): White Paper of the ACR TI-RADS Committee. J Am Coll Radiol 2017; 14:587-95.

Samargandy S, Ghoneim AH. Accuracy of ultrasound in predicting thyroid malignancy: a comparative analysis of the ACR TI-RADS and ATA risk stratifi cation systems. Archives of Endocrinology and Metabolism. 2024;68:e230245. doi:10.20945/2359-4292-2023-0245.

Li X, Hou X-J, Du L-Y, et al. Virtual touch tissue imaging and quantifi cation (VTIQ) combined with the American college of radiology thyroid imaging reporting and data system (ACR TI-RADS) for malignancy risk stratifi cation of thyroid nodules. Clin Hemorheol Microcirc 2019; 72:279-91.

Irini S. Hadjisavva, Roberto Dina, Michael A. Talias, et al. Prevalence of Cancer in Patients with Thyroid Nodules in the Island of Cyprus: Predictive Value of Ultrasound Features and Thyroid Autoimmune Status. Eur Thyroid J 2015; 4:123–128.

Chakhuttray, N. Accuracy of ultrasonography with ACR TI-RADS evaluation in patients with thyroid nodules undergoing surgery at Kantaralak hospital in Sisaket province. Sisaket Journal of Research and Health Development.2023;23-32.

Huang EYF, Kao NH, Lin SY, et al. Concordance of the ACR TI-RADS Classifi cation With Bethesda Scoring and Histopathology Risk Stratifi cation of Thyroid Nodules. JAMA Netw Open. 2023;6(9):e2331612. doi:10.1001/jamanetworkopen.2023.31612

Wongwattana, P., Pattarapongsant, P., Liangsupong, S., Sukontha, S., Khumsan, S., & Yimpornpipathpon, I. (2021). Diagnostic performance of ultrasonography with ACR TI-RADS in thyroid mass in HRH Princess Maha Chakri Sirindhorn Medical Center. Journal of

Medicine and Health Sciences, 28(3). 90-102.

ดาวน์โหลด

เผยแพร่แล้ว

2026-06-22

รูปแบบการอ้างอิง

1.
กีรติเรืองรอง ส. ความสอดคล้องของการวินิจฉัยก้อนต่อมไทรอยด์ด้วยคลื่นเสียงความถี่สูงในระบบ ACR TI-RADS กับผลตรวจชิ้นเนื้อทางพยาธิวิทยาจากการผ่าตัดต่อมไทรอยด์ ในโรงพยาบาลอุตรดิตถ์. HSCR [อินเทอร์เน็ต]. 22 มิถุนายน 2026 [อ้างถึง 6 กันยายน 2026];41(1):e280417 . available at: https://he02.tci-thaijo.org/index.php/hscr/article/view/280417

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