Short-Term Outcomes of Patients Undergoing Transcatheter Aortic Valve Replacement: Early Experience at Chulabhorn Cardiac Center
Keywords:
transcatheter aortic valve replacement (TAVR), transcatheter aortic valve implantation (TAVI), aortic stenosis, bioprosthetic heart valves, echocardiography, hemodynamics, treatment outcomes, complicationsAbstract
Background: Transcatheter aortic valve replacement (TAVR) has emerged as an alternative treatment for severe aortic stenosis in the past few decades. Chulabhorn Cardiac Center initiated a TAVR program in 2019. We herein report the initial 30-day outcomes and complications of the first 60 patients who underwent TAVR in Chulabhorn Cardiac Center.
Methods: This study involved the analysis of descriptive data for the first 60 patients who underwent TAVR from 2019 to 2021. The inclusion criteria were symptomatic severe aortic stenosis or asymptomatic severe aortic stenosis with an indication for valvular intervention according to current standard guidelines. The reported outcomes were retrospectively analyzed, including clinical outcomes, complications, and echocardiographic and hemodynamic changes pre- and post-TAVR.
Results: Sixty patients (47% female) were enrolled in this cohort. Their median Society of Thoracic Surgeons score was 3.7. The procedural success rate was 100%. The median in-hospital and 30-day follow-up mean pressure gradient was 9.9 and 11.2 mmHg, respectively, with 46 (93.4%) patients reportedly developing no to mild paravalvular leakage after the procedure. No patients died within the first 30 days after the procedure. With regard to periprocedural complications, 13 (21.7%) patients underwent permanent pacemaker implantation after the TAVR procedure because of new-onset high-grade or complete atrioventricular block. Four (6.6%) patients developed ischemic stroke after the TAVR procedure. Three (5.0%) patients developed a major vascular complication according to the VARC definition, among whom only one (1.7%) patient required surgical correction.
Conclusion: The immediate and 30-day outcomes in our initial 60 patients undergoing TAVR were favorable with a low complication rate.
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References
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