Effects of Phthalate Exposure in House Dust on Non-Communicable Diseases in the Elderly
Keywords:
Pollutant exposure, Plasticizers, Elderly, Non-communicable diseases, PhthalateAbstract
The causes of non-communicable diseases (NCDs) are multiple and varied. Over the past decade, however, environmental pollution has been identified as another cause of non-communicable diseases. Continued exposure to chemicals in plastics causes human health problems. Phthalate is a chemical that increases plastic softness and flexibility and can be found in a diverse range of industrial products and consumer goods. Because phthalate has no covalent bond with plastic, phthalate easily is released from plastic products and may contaminate water, food or even the air inside houses. Humans and animals can come into contact with phthalate from house dust in many ways. Previous studies have shown correlations between phthalate and undesirable health outcomes. When humans, particularly older adults who spend most of their time at home, come into contact with phthalate continually, this causes effects on non-communicable diseases, which are likely to increase. Therefore, the main goal of this article is to present the effects of phthalate on non-communicable diseases among the elderly, particularly respiratory, metabolic and cardiovascular diseases.
References
Cook CR, Halden RU. Ecological and health issues of plastic waste. In Plastic Waste and Recycling. Academic Press: Cambridge, MA, USA. 2020: 513-527. https://doi.org/10.1016/B978-0-12-817880-5.00020-7 PMid:31925800
Luo H, Sun G, Shi Y, Shen Y, Xu K. Evaluation of the Di (2-ethylhexyl) phthalate released from polyvinyl chloride medical devices that contact blood. Springerplus. [Online] 2014;29(3): 58. Available from: doi: 10.1186/2193-1801-3-58. PMID: 24516786; PMCID: PMC3916584 https://doi.org/10.1186/2193-1801-3-58 PMid:24516786 PMCid:PMC3916584
Grindler NM, Vanderlinden L, Karthikraj R, Kannan K, Teal S, Polotsky, AJ, et al. Exposure to phthalate, an endocrine disrupting chemical, alters the first trimester placental methylome and transcriptome in women. Sci. Rep. 2018; 8: 1-9. https://doi.org/10.1038/s41598-018-24505-w PMid:29666409 PMCid:PMC5904105
Bertelsen RJ, Carlsen KCL, Calafat AM, Hoppin JA, Håland GP, Mowinckel KH, et al. Urinary biomarkers for phthalates associated with asthma in Norwegian children. Environ Health Perspect. 2013;121: 251-256. https://doi.org/10.1289/ehp.1205256 PMid:23164678 PMCid:PMC3569683
Lind PM, Lind L. Circulating levels of bisphenol A and phthalates are related to carotid atherosclerosis in the elderly. Atherosclerosis. 2011;218: 207-213. https://doi.org/10.1016/j.atherosclerosis.2011.05.001 PMid:21621210
Kim JH, Park HY, Bae S, Lim Y-H, Hong Y-C. Diethylhexyl Phthalates Is Associated with Insulin Resistance via Oxidative Stress in the Elderly: A Panel Study. PLoS ONE. [Online] 2013;8(8): e71392. Available from: doi:10.1371/journal. pone.0071392 https://doi.org/10.1371/journal.pone.0071392 PMid:23977034 PMCid:PMC3747269
World Health Organization. The cost of a polluted environment: 1.7 million child deaths a year. [Online]. Geneva: WHO;2017 [cited 2021 Jun 1]. Available from:http://www.whoint/mediacentre/news/releases/2017/pollution-child-death/en/
Bae S, Hong YC. Exposure to bisphenol A from drinking canned beverages increases blood pressure: randomized crossover trial. Hypertension. 2015;65(2): 313-319. https://doi.org/10.1161/HYPERTENSIONAHA.114.04261 PMid:25489056
Dong R, Chen J, Zheng J, Zhang M, Zhang H, Wu M,et al. The role of oxidative stress in cardiometabolic risk related to phthalate exposure in elderly diabetic patients from shanghai. Environment International. [Online] 2018;121: 340-348. Available from: doi: 10.1016/j.envint.2018.09.028. https://doi.org/10.1016/j.envint.2018.09.028 PMid:30243182
Giuliani A, Zuccarini M, Cichelli A, Khan H, Reale M. Critical review on the presence of phthalates in food and evidence of their biological impact. International Journal of Environmental Research and Public Health. [Online] 2020;17(16): 1-43. Available from: doi.org/10.3390/ijerph17165655 https://doi.org/10.3390/ijerph17165655 PMid:32764471 PMCid:PMC7460375
Wang W, Leung AOW, Chu LH, Wong MH. Phthalates contamination in China: Status, trends and human exposure-with an emphasis on oral intake. Environ. Pollut. 2018;238: 771-782. https://doi.org/10.1016/j.envpol.2018.02.088 PMid:29625301
United States Environmental Protection Agency. America's Children and the Environment, 3rd ed.; Washington, DC: Office of Children's Health Protection. [Online] 2013. Available from: https://cdn.dal.ca/content/dam/dalhousie/pdf/faculty/science/emaychair/Reports%20Section/Emay_AmericasChildren.pdf
อรทัย พุมดวง. สภาวะที่มีผลต่อการชะออกมาของ di-(2-ethylhexyl) phthalate จากภาชนะพลาสติก บรรจุอาหารและขวดบรรจุนXาดื่ม [วิทยานิพนธ์หลักสูตร ปริญญาวิทยาศาสตรมหาบัณฑิต สาขาวิชาการจัดการ สิ่งแวดล้อม]. สงขลา: มหาวิทยาลัยสงขลานครินทร์. 2554.
Jia S, Sankaran G, Wang B, Shang H, Tan ST, Yap HM, et al. Exposure and risk assessment of volatile organic compounds and airborne phthalates in Singapore's Child Care Centers. Chemosphere. 2019;224: 85-92. https://doi.org/10.1016/j.chemosphere.2019.02.120 PMid:30818198
Lyche JL, Gutleb AC, Bergman Å, Eriksen GS, Murk AJ, Ropstad E, et al. Reproductive and developmental toxicity of phthalates. Journal of Toxicology and Environmental Health Part B. 2009;12: 225-249. https://doi.org/10.1080/10937400903094091 PMid:20183522
Bølling AK, Sripada K, Becher R, Bekö G. Phthalate exposure and allergic diseases: Review of epidemiological and experimental evidence. Environment International. . [Online] 2020;139. Available from: doi.org/10.1016/j.envint.2020.105706 https://doi.org/10.1016/j.envint.2020.105706 PMid:32371302
James-Todd T, Stahlhut R, Meeker JD, Powell SG, Hauser R, Huang T, et al. Urinary phthalate metabolite concentrations and diabetes among women in the National Health and Nutrition Examination Survey (NHANES) 2001-2008. Environ Health Perspect. 2012;120(9): 1307-1013. https://doi.org/10.1289/ehp.1104717 PMid:22796563 PMCid:PMC3440117
Trasande L, Attina TM. Association of exposure to di-2-ethylhexylphthalate replacements with increased blood pressure in children and adolescents. Hypertension. 2015;66(2): 301-308. https://doi.org/10.1161/HYPERTENSIONAHA.115.05603 PMid:26156503 PMCid:PMC4499862
กมลวรรณ พรมเทศ, บุณยฤทธิ์ ปัญญาภิญโญผล และสุพพัต ควรพงษากุล. ความสัมพันธ์ระหว่างธาเลต เอสเตอร์ในฝุ่นบ้านกับคุณลักษณะและสิ่งแวดล้อม ในบ้าน เขตพื้นที่กรุงเทพมหานคร ประเทศไทย. วารสารพิษวิทยาไทย. 2562;34(2): 27-45.
Bae S, Hong YC. Exposure to bisphenol A from drinking canned beverages increases blood pressure: randomized crossover trial. Hypertension. 2015;65(2): 313-319. https://doi.org/10.1161/HYPERTENSIONAHA.114.04261 PMid:25489056
Dan NP, Monica L, Gunilla W, Lars L. European Respiratory Journal Lung function decline in elderly in relation to phthalate metabolites and bisphenol A levels in serum: A 5-year prospective study. European Respiratory Journal. 2012;40: 4524.
Guo J, Han B, Qin L, Li B, You H, Yang J, et.al. Pulmonary toxicity and adjuvant effect of di- (2-exylhexyl) phthalate in ovalbumin-immunized BALB/c mice. PLoS One. [Online] 2012;7(6): e39008. Available from: doi: 10.1371/journal.pone.0039008. Epub 2012 Jun 12. PMID: 22701742; PMCID: PMC3373502. https://doi.org/10.1371/journal.pone.0039008 PMid:22701742 PMCid:PMC3373502
Lacey R, Rachel.The Impact of Bisphenol A and Phthalates on Allergy, Asthma, and Immune Function: A Review of Latest Findings. Curr Environ Health Rep. [Online] 2015;2(4): 379-387. Available from: doi:10.1007/s40572-015-0066-8. https://doi.org/10.1007/s40572-015-0066-8 PMid:26337065 PMCid:PMC4626318
สมศักดิ์ชุณหรัศมิ์.รายงานสถานการณ์ผู้สูงอายุไทย พ.ศ. 2550. กรุงเทพฯ: ทีคิวพี; 2551.
Wang X, Han B, Wu P, Li S, Lv Y, Lu J, et al. Dibutyl phthalate induces allergic airway inflammation in rats via inhibition of the Nrf2/TSLP/JAK1 pathway. Environmental Pollution. [Online] 2020; 267:115564. Available from: doi: 10.1016/j.envpol. 2020.115564 https://doi.org/10.1016/j.envpol.2020.115564 PMid:33254669
Stahlhut RW, Wijngaarden E, Dye TD, Cook S, Swan SH. Concentrations of urinary phthalate metabolites are associated with increased waistcircumference and insulin resistance in adult U.S. males. Environ Health Perspect. [Online] 2007. Available from: doi.org/10.1289/ehp.9882. https://doi.org/10.1289/ehp.9882 PMid:17589594 PMCid:PMC1892109
James-Todd TM, Huang T, Seely EW, Saxena AR. The association between phthalates and metabolic syndrome: The national health and nutrition examination survey 2001-2010. Environmental Health. [Online] 2016;15(1): 1-12. Available from: doi: 10.1186/s12940-016-0136-x https://doi.org/10.1186/s12940-016-0136-x PMid:27079661 PMCid:PMC4832560
Mariana M, Cairrao E. Phthalates Implications in the Cardiovascular System. Journal of Cardiovascular Development and Disease. [Online] 2020;7(3): 26. Available from: doi: 10.3390/ jcdd7030026. PMID: 32707888; PMCID: PMC7570088. https://doi.org/10.3390/jcdd7030026 PMid:32707888 PMCid:PMC7570088
Zhang W, Shen XY, Zhang WW, Chen H, Xu WP, Wei W. Di-(2-ethylhexyl) phthalate could disrupt the insulin signaling pathway in liver of SD rats and L02 cells via PPARγ. Toxicology and applied pharmacology. [Online] 2017; 316: 17-26. Available from: doi: 10.1016/j.taap.2016.12.010. Epub 2016 Dec 23. PMID: 28025108. https://doi.org/10.1016/j.taap.2016.12.010 PMid:28025108
Su TC, Hwang JJ, Sun CW, Wang SL. Urinary phthalate metabolites, coronary heart disease, and atherothrombotic markers. Ecotoxicology and environmental safety. [Online] 2019;173: 37-44. Available from: doi: 10.1016/j.ecoenv.2019.02.021. Epub 2019 Feb 10. PMID: 30753939. https://doi.org/10.1016/j.ecoenv.2019.02.021 PMid:30753939
Lind PM, Lind L. Circulating levels of bisphenol a and phthalates are related to carotid atherosclerosis in the elderly. Atherosclerosis. [Online] 2011; 218: 207-213. Available from: doi: 10.1016/j.atherosclerosis.2011.05.001. https://doi.org/10.1016/j.atherosclerosis.2011.05.001 PMid:21621210
Wiberg B, Lind PM, Lind L. Serum levels of monobenzylphthalate (mbzp) is related to carotid atherosclerosis in the elderly. Environmental Research. [Online] 2014;133: 348-352. Available from: doi: 10.1016/j.envres.2014.06.009. https://doi.org/10.1016/j.envres.2014.06.009 PMid:25036990
Wu W, Cao L, Zheng TT, Feng SY, Ma GW, He YY, et al. Prenatal phthalate exposure reduction through an integrated intervention strategy. Environmental Science and Pollution Research. [Online] 2021:1-9. Available from: doi.org/10.1007/s11356-021-14613-y
Chen CY, Chou YY, Lin SJ, Lee CC. Developing an intervention strategy to reduce phthalate exposure in Taiwanese girls. Science of the Total Environment. [Online] 2015;517: 125-131. Available from: doi: 10.1016/j.scitotenv.2015. 02.021. Epub 2015 Feb 25. PMID: 25725197. https://doi.org/10.1016/j.scitotenv.2015.02.021 PMid:25725197
Congqiao Y, Shelley AH, Liisa MJ, Jacob K, Linh VN, Miriam L. Phthalates: Relationships between Air, Dust, Electronic Devices, and Hands with Implications for Exposure. Diamond Environmental Science & Technology. [Online] 2020;54(13): 8186-8197. Available from: doi: 10.1021/acs.est.0c00229 https://doi.org/10.1021/acs.est.0c00229 PMid:32539399
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Chulabhorn Royal Academy
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
บทความที่ได้รับการตีพิมพ์เป็นลิขสิทธิ์ของราชวิทยาลัยจุฬาภรณ์
ข้อความที่ปรากฏในบทความแต่ละเรื่องในวารสารวิชาการเล่มนี้เป็นความคิดเห็นส่วนตัวของผู้เขียนแต่ละท่านไม่เกี่ยวข้องกับราชวิทยาลัยจุฬาภรณ์ และคณาจารย์ท่านอื่น ในราชวิทยาลัยฯ แต่อย่างใด ความรับผิดชอบองค์ประกอบทั้งหมดของบทความแต่ละเรื่องเป็นของผู้เขียนแต่ละท่าน หากมีความผิดพลาดใด ๆ ผู้เขียนแต่ละท่านจะรับผิดชอบบทความของตนเองแต่ผู้เดียว
