BCOR-CCNB3 fusion-positive soft tissue sarcoma: A case report and literature review

Authors

  • Siripuk Sawetchaikul Department of Surgery, Nopparat Rajathanee Hospital Bangkok, Thailand
  • Tasama Pusongchai Department of Pediatrics, Thammasat University Hospital, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand
  • Utairat Chaumrattanakul Department of Radiology, Thammasat University Hospital, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand
  • Jutatip Kintarak Department of Pathology and Forensic Medicine, Thammasat University Hospital, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand
  • Artit Jinawath Department of Pathology, Ramathibodi Hospital, Mahidol University Bangkok, Thailand
  • Pacharapan Surapolchai Department of Pediatrics, Thammasat University Hospital, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand
  • Pakatip Sinlapamongkolkul Department of Pediatrics, Thammasat University Hospital, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand

Keywords:

BCOR-CCNB3 sarcoma, undifferentiated sarcoma, acute myeloblastic leukemia

Abstract

BCOR-CCNB3 sarcoma is one of a group of undifferentiated sarcomas. The objective of this case report was to describe the clinical and pathological data of a patient with this tumor. Our patient was a 14-year-old male adolescent with right flank pain. Imaging revealed a psoas muscle mass lesion. Histology and gene expression were suggestive of BCOR-CCNB3 sarcoma. Chemotherapy, surgery, and radiotherapy were used according to the Ewing sarcoma protocol in Thailand. Unfortunately, our patient died from acute myeloblastic leukemia (M5) without remission despite chemotherapy.

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Published

2023-10-01

How to Cite

1.
Sawetchaikul S, Pusongchai T, Chaumrattanakul U, Kintarak J, Jinawath A, Surapolchai P, Sinlapamongkolkul P. BCOR-CCNB3 fusion-positive soft tissue sarcoma: A case report and literature review. J Chulabhorn Royal Acad [Internet]. 2023 Oct. 1 [cited 2024 Nov. 24];5(4):243-52. Available from: https://he02.tci-thaijo.org/index.php/jcra/article/view/258530

Issue

Vol. 5 No. 4 (2023): October - December

Section

Academic Articles

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