Effectiveness of Whole dose and Split dose regimen of bowel preparation for colonoscopy in Banphai hospital, a retrospective study
Keywords:
Colonoscopy, Bowel preparation, Cecal intubation, Polyp detection rate, Colon cancerAbstract
This study compared the effectiveness of bowel preparations in patients who were undergoing colonoscopy in Banphai Hospital between October and December 2020, a total of 179 patients assigned to receive 2 liters of preparation regimen (morning before the procedure; Whole dose, n = 96) and 1 liter of preparation regimen followed by another 1 liter on next day (day before the procedure at 18:00 and day of the procedure at 5:00; split dosing bowel preparation, n=83). The primary endpoint was the quality of whole colon cleansing according to the Boston bowel preparation scale (BBPS), Polyp detection, Cecal intubation time, and total treatment cost were the secondary outcomes. This was a single-center retrospective study. The data were analyzed with descriptive statistics, such as Percentage and Frequency, which used to summarize the qualitative data (Categorical variables), while Means and Standard deviations (SD) are used to summarize continuous variables. Data were collected from the hospital's electronic database. The results showed that patients who received the Whole dose preparation colon cleaning than those who received the Split dose preparation (7.97±1.22 vs. 8.06±1.45, P=0.647), there was statistically no significant difference. The polyp detection rate was a greater, but not statistically significant difference in the whole dose group (25.7% และ 27.1% P=0.648). Diverticulosis was lower, but not statistically significant difference in the whole dose group (11.7% vs. 9.4% P=0.648). The mean of cecal intubation time was a greater, but not statistically significant difference in the whole dose group (6 (4, 8) mins and 5 (4, 8) mins P=0.534). The expenditure mean was lower, but not statistically significant different in whole dose group (5,421 (5,617, 7,347) baht vs. 5,679 (5,547, 6,423) baht) (P=0.447)). These findings suggest that there was obviously no superior of both bowel preparation. Which method to choose depends on the suitability of each hospital context.
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