Role of Continuous Renal Replacement Therapy for Acute kidney injury treatment in COVID-19 patients: case study

Abstract

Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-inflammation, acute respiratory distress syndrome, multiple organ failure and acute kidney injury (AKI). Patient develops severe AKI, renal replacement therapy (RRT) should be considered. Recently, we had a critically ill COVID-19 patient who developed severe AKI and needed continuous RRT (CRRT). In this study, we report our unique experience with AKI in COVID-19 patients. A reported case was performed in COVID-19 patients admitted to the Khon Kaen Hospital from April to May 2021. Information regarding demographics, co-morbidities, medications, clinical and laboratory data, and outcomes was collected from the electronic medical records. Both cases showed complication in respiratory complication and AKI. Hemodialysis and CRRT gave improvement of kidney function test, control fluid and electrolytes and also decrease acidosis. Due to unstable hemodynamic status in critically ill patients, CRRT should be the first choice for severe AKI in COVID-19 patients. We suggest prevention of clinical infection and control during administration of CRRT in the acute phase of COVID-19 patients with AKI and respiratory infection on top.