The Influences of Depression, Identity of Symptoms, Smoking Status, and Number of Daily Drug Doses on Adherence to Inhaled Long-Acting Bronchodilators in Patients with Chronic Obstructive Pulmonary Disease

Main Article Content

Thonaput Sumonviwat
Doungrut Wattanakitkrileart
Kanaungnit Pongthavornkamol
Nuttapol Rittayamai

Abstract

Purpose: This study aimed to examine the influences of depression, identity of symptoms, smoking status, and number of daily drug doses on adherence to inhaled long-acting bronchodilators in patients with chronic obstructive pulmonary disease (COPD).


Design: Predictive correlational study design.


Methods: The study samples included 173 patients with COPD who came for follow-up visits at COPD clinic of a tertiary hospital in Bangkok. Data were collected by questionnaires including demographic data questionnaire, Medication Adherence Report Scale, the Brief Illness Perception Questionnaire (identity item), and the Center for Epidemiological Studies-Depression Scale. Data were analyzed using descriptive statistics and logistic regression analysis.


Main findings: The results showed that majority (93.6%) were male with average age of 73.32 years (SD = 9.27). Seventy-four percent of the participants were adherent to inhaled long-acting bronchodilators, while depression, identity of symptoms, smoking status, and number of daily drug doses together contributed for 15.1% of variation on adherence to inhaled long-acting bronchodilators in patients with COPD. It was also found that only depression could predict inhaled therapy adherence in patients with COPD (OR = .91; 95%CI = .86, .95, p < .001).


Conclusion and recommendations: The influences of depression associated with non-adherence to inhaled long-acting bronchodilators in patients with COPD. Hence, nurses should pay attention to assess, prevent and manage depression in patients with COPD in order to promote medication adherence in patients with COPD.

Article Details

How to Cite
Sumonviwat, T., Wattanakitkrileart, D., Pongthavornkamol, K., & Rittayamai, N. (2019). The Influences of Depression, Identity of Symptoms, Smoking Status, and Number of Daily Drug Doses on Adherence to Inhaled Long-Acting Bronchodilators in Patients with Chronic Obstructive Pulmonary Disease. Nursing Science Journal of Thailand, 37(1), 45–58. Retrieved from https://he02.tci-thaijo.org/index.php/ns/article/view/183623
Section
Research Papers

References

1. Global Initiative for Obstructive Lung Disease. GOLD 2017 Global strategy for the diagnosis, management and prevention of COPD [Internet]. California: GOLD; 2017 [cited 2017 Feb 5]: Available from: https://goldcopd.org/gold-2017-global-strategy-diagnosis-management-prevention-copd/

2. National Health Security Office. NHSO area 4 (Saraburi) collaborated with Khon Kaen University and Healthcare Accreditation Institute (Public Organisation) construct treatment mechanisms, prevent exacerbations in asthma and COPD [Internet]. Bangkok: NHSO; 2013 [cited 2017 Mar 26]: Available from: https://www.nhso.go.th/frontend/NewsInformationDetail.aspx?newsid=Njgy. (in Thai).

3. Toy EL, Beaulieu NU, McHale JM, Welland TR, Plauschinat CA, Swensen A, et al. Treatment of COPD: relationships between daily dosing frequency, adherence, resource use, and costs. Respir Med. 2011;105(3):435-41.

4. Nishi SPE, Maslonka M, Zhang W, Kuo YF, Sharma G. Pattern and adherence to maintenance medication use in medicare beneficiaries with chronic obstructive pulmonary disease: 2008-2013. Chronic Obstr Pulm Dis. 2018;5(1):16-26.

5. Wells K, Pladevall M, Peterson EL, Campbell J, Wang M, Lanfear DE, et al. Race-ethnic differences in factors associated with inhaled steroid adherence among adults with asthma. Am J Respir Crit Care Med. 2008;178(12):1194-201.

6. Albrecht JS, Khokhar B, Huang TY, Wei YJ, Harris I, Moyo P, et al. Adherence and healthcare utilization among older adults with COPD and depression. Respir Med. 2017;129:53-8.

7. Yohannes AM, Alexopoulos GS. Depression and anxiety in patients with COPD. Eur Respir Rev. 2014;23(133):345-9.

8. Broadbent E, Petrie KJ, Main J, Weinman J. The brief illness perception questionnaire. J Psychosom Res. 2006;60(6):631-7.

9. Tiemensma J, Gaab E, Voorhaar M, Asijee G, Kaptein AA. Illness perceptions and coping determine quality of life in COPD patients. Int J Chron Obstruct Pulmon Dis. 2016;11:2001-7.

10. Weldam SW, Lammers JW, Decates RL, Schuurmans MJ. Daily activities and health-related quality of life in patients with chronic obstructive pulmonary disease: psychological determinants: a cross-sectional study. Health Qual Life Outcomes. 2013;11:190. doi: 10.1186/1477-7525-11-190.

11. Koehorst-Ter Huurne K, Kort S, van der Palen J, van Beurden WJ, Movig KL, van der Valk P, et al. Quality of life and adherence to inhaled corticosteroids and tiotropium in COPD are related. Int J Chron Obstruct Pulmon Dis. 2016;11:1679-88.

12. Hayes-Watson C, Nuss H, Tseng TS, Parada N, Yu Q, Celestin M, et al. Self-management practices of smokers with asthma and/or chronic obstructive pulmonary disease: a cross-sectional survey. COPD Res Pract. 2017;3:3. doi: 10.1186/s40749-017-0022-0.

13. Toh MR, Teo V, Kwan YH, Raaj S, Tan SY, Tan JZ. Association between number of doses per day, number of medications and patient's non-compliance, and frequency of readmissions in a multi-ethnic Asian population. Prev Med Rep. 2014;1:43-7.

14. Horne R, Hankins M. The medication adherence report scale. Brighton, England: Center for Health Care Research; 2002.

15. Wiriyachot A, Wattanakitkrileart D, Charoenkitkarn V, Dejsomritrutai W. Influences of perceived medication necessity, medication concern, satisfaction with information received, and experience of exacerbation on adherence of inhaled combined bronchodilator and corticosteroid therapy in patients with chronic obstructive pulmonary disease. Journal of The Royal Thai Army Nurses. 2016;17(3):187-196. (in Thai).

16. Cohen JL, Mann DM, Wisnivesky JP, Horne R, Leventhal H, Musumeci-Szabó TJ, et al. Assessing the validity of self-reported medication adherence among inner-city asthmatic adults: the Medication Adherence Report Scale for Asthma. Ann Allergy Asthma Immunol. 2009;103(4):325-31.

17. Radloff LS. The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1(3):385-401.

18. Kuptniratsaikul V, Katumarn P. The study of the Center for Epidemiologic Studies-Depression scale (CES-D) in Thai People. Siriraj Medical Journal. 1997;49(5):442-8. (in Thai).

19. Smarr KL, Keefer AL. Measures of depression and depressive symptoms: Beck Depression Inventory-II (BDI-II), Center for Epidemiologic Studies Depression Scale (CES-D), Geriatric Depression Scale (GDS), Hospital Anxiety and Depression Scale (HADS), and Patient Health Questionnaire-9 (PHQ-9). Arthritis Care Res (Hoboken). 2011;63 Suppl 11:S454-66.

20. Polit DF, Beck CT. Essentials of nursing research: apraising evidence for nursing practice. 7th ed. Philadelphia: Lippincott Williams & Wilkins; 2010.

21. Oung AB, Kosirog E, Chavez B, Brunner J, Saseen JJ. Evaluation of medication adherence in chronic disease at a federally qualified health center. Ther Adv Chronic Dis. 2017;8(8-9):113-20.

22. Albrecht JS, Park Y, Hur P, Huang TY, Harris I, Netzer G, et al. Adherence to maintenance medications among older adults with chronic obstructive pulmonary disease. The role of depression. Ann Am Thorac Soc. 2016;13(9):1497-504.

23. Aujla N, Walker M, Sprigg N, Abrams K, Massey A, Vedhara K. Can illness beliefs, from the common-sense model, prospectively predict adherence to self-management behaviours? A systematic review and meta-analysis. Psychol Health. 2016;31(8):931-58.

24. Ágh T, Inotai A, Mészáros Á. Factors associated with medication adherence in patients with chronic obstructive pulmonary disease. Respiration. 2011;82(4):328-34.