Factors Predicting Physical Deterioration in Patients with COVID-19 and Sepsis

Main Article Content

Bachchakhan Pathan
Wimolrat Puwarawuttipanit
Pichitra Lekdamrongkul
Yong Rongrungruang


Purpose: This study aimed to examine the predictive power of age, comorbidity, body mass index, smoking history, and blood glucose level on physical deterioration in patients with COVID-19 patients and sepsis.

Design: Predictive study design.

Methods: The study sample consisted of 147 male and female patients infected with COVID-19 and having sepsis who met the inclusion and exclusion criteria. Data were collected using recording forms for personal information and illness history as well as information about admission and discharge, Charlson Comorbidity Index, and the National Early Warning 2 score. Data were analyzed using descriptive statistics and binary logistic regression analysis.

Main findings: Age, comorbidity, body mass index, smoking history, and level of blood glucose could together predict 43% of physical deterioration in patients with COVID-19 and sepsis (Nagelkerke R2 = .43). All study factors, except level of blood glucose, could significantly predict physical deterioration. Comorbidity showed greatest predictive power; that is, those with comorbidity index higher than 3 would have 10.45 times more chance to have physical deterioration compared to those with index equal to or less than 3 (OR = 10.45; 95%CI = 3.40, 32.13, p < .001).

Conclusion and recommendations: Age, comorbidity, body mass index, and smoking history could predict physical deterioration in patients with COVID-19 and sepsis, Thus, nurses should assess these significant factors for surveillance and develop appropriate nursing intervention to prevent such physical deterioration during hospitalization.

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How to Cite
Pathan, B., Puwarawuttipanit, W. ., Lekdamrongkul, P. ., & Rongrungruang, Y. (2023). Factors Predicting Physical Deterioration in Patients with COVID-19 and Sepsis. Nursing Science Journal of Thailand, 41(3), 20–33. Retrieved from https://he02.tci-thaijo.org/index.php/ns/article/view/260982
Research Papers


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