Risk Factors of Acute Myocardial Infarction in Young Adults: An Integrative Literature Review

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Thipsuda Phomdontre
Jintana Damkliang


Introduction: The purpose of this integrative literature review was to evaluate potential risk factors for acute myocardial infarction in young adults. This review was based on studies extracted from electronic databases, including CINHAL, PubMed, THAIJO, ProQuest, and ScienceDirect between 2010 and 2020. Thirteen articles with full-text published in English and Thai met the inclusion criteria. Total articles were then selected based on the quality of Joanna Briggs Institute critical appraisal. The result of this integrative literature review shows that acute myocardial infarction in young adults was reported in age between 15 and 45 years. Risk factors were grouped in two types (1) non-modifiable risk factors include age, gender, family history of coronary diseases, and (2) modifiable risk factors include dyslipidemia, obesity, hypertension, diabetes mellitus, cigarette smoking, alcohol drinking, drug abuse, including Amphetamine, Cannabis, physical inactivity, having high fat diets, inadequate vegetable and fruit consumption, hyperhomocysteinemia, and stress. Conclusion: This result could be used as basis information for healthcare providers to promote health
in order to prevent risk factors for acute myocardial infarction in young adults. In addition, a study regarding
to association of risk factors found in this study on acute myocardial infarction in young adults is needed to be approved.


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Phomdontre, T., & Damkliang, J. (2021). Risk Factors of Acute Myocardial Infarction in Young Adults: An Integrative Literature Review. ongklanagarind ournal of ursing, 41(3), 99-108. etrieved from https://he02.tci-thaijo.org/index.php/nur-psu/article/view/251229


World Health Organization. World health statistics 2020: Monitoring health for the SDGs, sustainable development goals. Geneva: World Health; 2020.

Sricharan KN, Rajesh S, Rashmi, et al. Study of acute myocardial infarction in Young Adults: Risk factors,

presentation and angiographic findings. JCDR. 2012; 6(2): 257-60.

Strategy and Planning Division [Internet]. Bangkok: 2018 [cited 2020 Dec 15]. Available from: https://bps.moph.go.th/new_bps/.

Piromsit N, Srikulsiripanno J, Nurakhe A, et al. Factors influencing cardiovascular disease prevention behaviors among the risk group in SuphanBuri Province, Thailand. HCU JOURNAL 2018; 22(43-44): 55-69. Thai.

Chaiwong N, Bonkhonthod P. Factors preventive behaviors for coronary heart disease among persons at risk to disease. Journal of Nursing and Health Care. 2019; 37(2): 6-15. Thai.

Jamfa W, Chumpeeruang S, Rueangphut P, et al. Depression and quality of life among elderly living in Muang NakhonSawan Province. Boromarajonani College of Nursing, Uttaradit Journal. 2019; 11(2): 259-71. Thai.

Hat Yai Hospital Statistics Agency. (2017-2019). Statistics on Ward Accident and Hospital Emergency Hat Yai 2017-2019.

Mitsungnern T, Sukeepaisarncharoen W, Kiatchusakul S, et al. Acute myocardial infarction in the young age group patients in Srinagarind Hospital: A Descriptive Study. Srinagarind Med J. 2013; 28(3): 274-81. Thai.

Cheema FM, Cheema HM, Akram Z. Identification of risk factors of acute coronarysyndromein young patients between 18-40 years of age at a teaching hospital. Pak J Med Sci. 2020; 36(4): 821-24. doi: 10.12669/pjms.36.4.2302.

Kalimuddin M, Ahmed N, Badiuzzzaman M, et al. AMI in very young (aged ≤ 35 years) Bangladeshi patients: Risk factors & coronary angiographic profile. CTRSC. 2016; 13: 1-5. doi: http://dx.doi.ong/10.1016/j.ctrsc.2015.11.003.

Sricharan KN, Rajesh S, Rashmi, et al. Study of Acute Myocardial Infarction in Young Adults: Risk factors, presentation and angiographic findings. JCDR. 2012; 6(2): 257-60.

Dahal K, Karki P, Maskey R, et al. Risk factors of acute myocardial infarction in young adults of Nepalese population. IJMDC. 2018; 2(3): 80-5. doi: http://doi.org/10.24911/IJMDC.61-1529054592.

Deshmukh PP, Singh MM, Deshpande MA, et al. Clinical and angiographic profile of very young adults presenting with first acute myocardial infarction: Data from a tertiary care Center in Central India. Indian Heart J. 2019; 71(5): 418-21. doi: 10.1016/j.ihj.2019.12.004.

Sinha SK, Krishna V, Thakur R, et al. Acute myocardial infarction in very young adults: A clinical presentation, risk factors, hospital outcome index, and their angiographic characteristics in North India-AMIYA Study. ARYA Atheroscler. 2017; 13(2): 79-87.

Bhardwaj R, Kandoria A, Sharma R. Myocardial infarction in young adults-risk factors and pattern of coronary artery involvement. Niger Med J. 2014; 55(1): 44-7. doi: 10.4103/0300-1652.128161.

Sarr M, Ba DM, Ndiaye MB, et al. Acute coronary syndrome in young Sub-Saharan Africans: A prospective study of 21 cases. BMC Cardiovascular Disorders. 2013; 13(1): 113-8. doi: 10.1186/1471-2261-13-118.

Callachan EL, Alsheikh-Ali AA, Wallis LA. Analysis of risk factors, presentation, and in-hospital events of very young patients presenting with ST-elevation myocardial infarction. J Saudi Heart Assoc. 2017; 29(4): 270-5. doi: 10.1016/j.jsha.2017.01.004.

Wani MI, Rashid A, Beig JR, et al. Acute coronary syndrome (ACS) in the young: Angiographic features and risk factor analysis of patients with ACS before the Age of 35 Years. IJSS. 2017; 5(4): 244-8. doi: 10.17354/ijss/2017/373.

Tamrakar R, Bhatt YD, Kansakar S, et al. Acute myocardial infarction in young adults: Study of risk factors, angiographic features and clinical outcome. NHJ. 2013; 10(1): 12-6. doi: https://doi.org/10.3126/njh.v10i1.9740.

Haque A, Siddiqui A, Rahman S, et al. Acute coronary syndrome in the young-risk factors and angiographic pattern. Cardiovasc J. 2010; 2(2): 175-8. doi: https://doi.org/10.3329/cardio.v2i2.6635.

Balakrishnan VK, Chopra A, Muralidharan TR, et al. Clinical profile of acute coronarysyndrome among young adults. International. IJCCR. 2018; 4(1): 52-9.

Deora S, Kumar T, Ramalingam R, et al. Demographic and angiographic profile in premature cases of acute coronary syndrome: analysis of 820 young patients from South India. Cardiovasc Diagn Ther. 2016; 6(3): 193-8. doi: 10.21037/cdt.2016.03.05.

Pathak V, Ruhela M, Chadha N, et al. Risk factos, angiographic characterization and prognosis in young adults presented with acute coronary syndrome at a tertiary care center in North India. BMR Medicine. 2016; 3(60): 1-5.

Faisal AW, Ayub M, Waseem T, et al. Risk factors in young patients of Acute myocardial infarction. J Ayub Med Coll Abbottabad. 2011; 23(3): 10-3.

Mukherjee D, Hsu A, Moliterno DJ, et al. Risk factors for premature coronary artery disease and determinants of adverse outcomes after revascularization in patients ≤ 40 years old. Am J Cardiol. 2003; 92(12): 1465-7. doi: 10.1016/j.amjcard.2003.08.062.

Jamil G, Jamil M, Alkhazraji H, et al. Risk factor assessment of young patients with acute myocardial

infarction.Am J Cardiovasc Dis. 2013; 3(3): 170-4.

Daranisorn S, Boonchuang P, Pinyokun. Effects of transitional care program on health behaviors and functional capacity among acute coronary syndrome patients. Nursing J. 2013; 40(2): 103-12. Thai.

Phanthuwethy N, Absuwan N, Apinya T. Risk assessment and management manual cardiovascular disease. Nonthaburi: The Agricultural Cooperative Federation of Thailand Limited; 2014. Thai.

Draz EI, Oreby MM, Elaheikh EA, et al. Marijuana use in acute coronary syndromes. Am J Drug Alcohol

Abuse. 2017; 43(5): 576-82. doi: 10.1080/00952990.2016.1240800.

Neeraphattanakul S. Factors associated with acute coronary syndrome prevention behavior in diabetes and hypertension patients in Chonburi Province [master’s thesis].[Chonburi]: Burapha University; 2018. 92 p.