ความชุกและปัจจัยเสี่ยงต่อการเกิดกระดูกสันหลังหักในสตรีชนบท หมู่บ้านทุ่งเหียง อ.สนามชัยเขต จ.ฉะเชิงเทรา ประเทศไทย

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สิทธิกร กุลประเสริฐศรี

Abstract

Vertebral fractures usually are caused by osteoporosis. Severe fractures can cause significant pain leading  to inability to perform daily living activities and life-threatening conditions especially in the elderly patients. Since  there will be approximately 15.2% elderly by the year 2020 the prevalence of vertebral fracture will become themajor   roblem. Until now there is no epidemiological data of vertebral fracture in Thailand. Objective: To identify the  prevalence and risk factors of vertebral fracture in Thai women Study Design: Cross-sectional study Materialand  Methods: Data collection was conducted in women aged ≥ 40 years old in Moo 18 Ban Tunghieng village Chachreongsao hailand which included demographic clinical and health behavior information using standardizedquestionnaire  bone mass density (BMD) using QUS and T-L spine X-ray. Vertebral fracture at T4-L5 level was classified using Genant’s criteria. Results and Disscussion: A total of 139 participants aged between 40 and 82 years (mean  = 54 ± 10.1) were enrolled into this study. The prevalence of vertebral fracture was approximately 28% which was  remarkably high compared to those of other countries. The fractures were commonly found at the level of T11-L2 most of which were anterior compression and biconcave fractures. In contrast to previous studies osteoporosis was  not a significant risk factor of vertebral fracture in the population. The only factor identified to be associated with vertebral fractures was menopausal period. Using multivariate analysis those who had menopause ≥ 1 year was  2.5-time greater risk of having vertebral fracture. Conclusions: In addition to the effect of menopause high prevalence of vertebral fracture in this study may be due to their agricultural work activities. In conclusion the prevention and control strategies of vertebral fracture should be considered in this specific group.

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นิพนธ์ต้นฉบับ (Original Article)