ความชุกของภาวะติดเชื้อในทารกคลอดก่อนกำหนดอายุครรภ์ตั้งแต่ 32 สัปดาห์ ในโรงพยาบาลพระมงกุฎเกล้า

Abstract

Preterm infants have high risk for infection. A guideline for management of preterm infants was developed. Objective: To determine the prevalence of neonatal sepsis in preterm infants of gestational age ≥ 32 weeks  and rate of readmission after using the guideline. Methodology: Preterm infants of gestational age ≥ 32 weeks were recruited. Infants were investigated and treated based on the guideline for preterm infants. All infants were  followed-up at 1 month of age. Statistical analysis: t-test or Mann Whitney test and Chi-square or Fisher exact  test are used for analysis as appropriate. Result: There were 171 infants of which 87 were infected. The prevalence  of neonatal infection was 50.9%. Infants of infected group had lower gestational age and birth weight than  those of non-infected group. Prevalence of premature rupture of membrane > 18 hours was significantly higherin  infected group. There were no infant who received no antibiotics readmitted to the hospital. Conclusion: Prevalence of sepsis in preterm infants of gestational age ≥ 32 weeks is high. Factors related to infection are gestational age birth weight and history of PROM > 18 hours. Guideline for management of preterm infants is safe and useful.